CEA vaccines

A Bhagat, HK Lyerly, MA Morse… - Human Vaccines & …, 2023 - Taylor & Francis
immune response to tumor associated CEA without inducing … a Tat-CEA fusion protein
also led to preventative anti-tumor … , alteration of CEA antigens, or co-expression of immune

[PDF][PDF] Expression Mechanism of Immunogenic Cell Death-Related Molecules in Colorectal Cancer

R Zhang - J Gstro Hepato - jajgastrohepto.org
… even younger and younger [1-2]. For patients diagnosed with … eliciting tumor-specific immune
responses against live tumor … induce ICD and trigger the body’s anti-tumor immunity is an …

Protein transduction domain-mediated influenza NP subunit vaccine generates a potent immune response and protection against influenza virus in mice

Y Yin, BB Li, L Zhou, J Luo, X Liu, S Wang… - Emerging Microbes & …, 2020 - Taylor & Francis
… transduction domain (PTD) TAT protein from human … immune response induced by TAT-NP
in intranasally vaccinated mice. Six groups of BALB/c mice were vaccinated three times at two

Nanodiscs: a versatile nanocarrier platform for cancer diagnosis and treatment

J Bariwal, H Ma, GA Altenberg, H Liang - Chemical Society Reviews, 2022 - pubs.rsc.org
… of full-length anti-CEA antibody using NDs modified with doping of … in both animal models
indicates amplified immune response … , leading to strong anti-tumor effects against both tumors. …

[PDF][PDF] mRNA-based therapeutics to induce immunity against cancer and infectious diseases

L Van Hoecke - 2020 - biblio.ugent.be
… In this thesis we applied two types of experimental mRNA-based … the induction of
antigen-specific immune responses by lipid-… In summary, the chemical modification of nucleotides …

Biomaterials‐Based Vaccinatio in Cancer Therapy

R Sharma, R Malviya, S Sundram - Integration of Biomaterials …, 2023 - Wiley Online Library
… Antigen-induced immune responses are those that are … CEA (CEA) lacking its signal
sequences, calreticulin (CRT), and … , S., Therapeutic anti-tumor immunity triggered by injections of …

Dendritic cell vaccines for cancer therapy: fundamentals and clinical trials

GG Romagnoli, R Kaneno - … Bench to Bedside Immunotherapy of Cancers, 2021 - Springer
… immunosurveillance and regulation of the immune system [9, 10], … allogeneic DC is able to
change the natural history of the … showed an ability to induce specific T response to CEA [146]. …

[PDF][PDF] Ovarian cancer treatment with a liposome formulated mRNA vaccine in combination with (neo-) adjuvant chemotherapy: Study protocol of the OLIVIA phase I …

ST Paijens, AKL Reyners, M de Bruyn… - Tumor immunology and … - research.rug.nl
… Targeting the immune system to reduce tumor-induced immune suppressive cells; … Modification
of CEA with both CRT and TAT PTD induces potent anti-tumor immune responses in RNA…

[PDF][PDF] From molecular optimization to therapy combination: novel strategies to improve cancer DNA vaccines

A Lopes - 2019 - dial.uclouvain.be
… Harnessing DNA-induced immune responses for improving … cells from the immune control,
because of different modifications in the … vaccines in inducing a protective anti-tumor immune

Nanodiscs: Game changer nano-therapeutics and structural biology tools

AO Elzoghby, O Samir, A Soliman, S Solomevich, M Yu… - Nano Today, 2023 - Elsevier
… bearing carcinoembryonic antigen (CEA) transfected E0771 … can elicit a strong T cell immune
response against tumor Ag … promote efficient anti-tumor CD8 + T cell response. CpG DNA …