Placental lipid transport and content in response to maternal overweight and gestational diabetes mellitus in human term placenta

L Song, N Wang, Y Peng, B Sun, W Cui - Nutrition, Metabolism and …, 2022 - Elsevier
transport capacities [10]. However, placental fatty acid (FA) metabolism in response to
maternal obesity … their receptors are believed to modulate key intracellular signalling pathways …

Altered materno-fetal transfer of 13C-polyunsaturated fatty acids in obese pregnant women

A Gázquez, MT Prieto-Sánchez, JE Blanco-Carnero… - Clinical nutrition, 2020 - Elsevier
Maternal obesity at conception is considered a major predictor of offspring … We investigated
the in vivo materno-fetal transfer of fatty acids (FAs) in obese pregnant women using stable …

Placental mobilization of free fatty acids contributes to altered materno-fetal transfer in obesity

B Hirschmugl, S Perazzolo, BG Sengers… - … Journal of Obesity, 2021 - nature.com
… are involved in the cellular uptake of free fatty acids (FFA). … Although lack of direct evidences,
maternal obesity alters at … pathophysiological metabolic conditions, such as maternal obesity

Impact of maternal obesity on the metabolism and bioavailability of polyunsaturated fatty acids during pregnancy and breastfeeding

D Álvarez, Y Muñoz, M Ortiz, M Maliqueo… - Nutrients, 2020 - mdpi.com
… Considering the consequences of an abnormal FA supply to offspring induced by maternal
obesity, we aimed to review the effects of obesity on the metabolism and bioavailability of FA …

Effect of maternal obesity and gestational diabetes on placental fatty acid uptake, metabolism and transfer to the fetus

MT Segura Moreno - 2019 - digibug.ugr.es
… Our results showed that maternal excessive pre-conceptional … in the uptake, metabolism
and transfer of fatty acids through … of food modulates caloric intake (1), and the metabolic status …

[HTML][HTML] Adipose tissue development and lipid metabolism in the human fetus: The 2020 perspective focusing on maternal diabetes and obesity

G Desoye, E Herrera - Progress in lipid research, 2021 - Elsevier
… (GDM) or maternal obesity are characterized by excessive fat … the identification of novel fatty
acid classes and derivatives. It … to review maternal or placental lipid metabolism or maternal-…

Maternal fatty acid metabolism in pregnancy and its consequences in the feto-placental development

AK Duttaroy, S Basak - Frontiers in Physiology, 2022 - frontiersin.org
fatty acid transport and metabolism, and their roles in feto-placental growth and development.
The review also highlights how maternal fat metabolism modulates … do full-term neonates. …

… fatty acid transporter FABP1 and increased isoprostanes and neuroprostanes in the human term placenta: implications for inflammation and birth weight in maternal …

L Belcastro, CS Ferreira, MA Saraiva, DB Mucci… - Nutrients, 2021 - mdpi.com
… imposed by maternal obesity disrupts the cross-talk between maternal signals and … Uptake
and metabolism of essential fatty acids, particularly DHA, is impaired in placentas from obese

Placental function in maternal obesity

AC Kelly, TL Powell, T Jansson - Clinical Science, 2020 - portlandpress.com
… factors and hormones in maternal obesity modulate placental function. … fatty acid uptake
transporters [165,166] in human trophoblasts have led to the proposal that placental metabolism

[HTML][HTML] Maternal obesity results in decreased syncytiotrophoblast synthesis of palmitoleic acid, a fatty acid with anti-inflammatory and insulin-sensitizing properties

V Ferchaud-Roucher, K Barner, T Jansson… - The FASEB …, 2019 - ncbi.nlm.nih.gov
… (14, 15) but rather by an alteration in lipid esterification and down-regulation in FA oxidation
(16), suggesting that the placenta of obese mothers may be modulating delivery of lipids to …