… virulence factors that contribute to fungal intracellular survival. … confirmed that live fungus
was required to modulate the … The effect of replicative aging on phagosomal maturation in …

… CR can influence the replicative lifespan (RLS) of various organisms by modulating several
… and greater virulence of MATα cells. Our data further encourage efforts to characterize …

… To investigate the effects of replicative aging on gene … backgrounds and examines the effect
of MitoTEMPO treatment … respiration is crucial for cryptococcal virulence, in vivo resilience, …

… virulence factors or how replicative aging can contribute to pathogenesis. Cryptococcus
neoformans … involved in virulence and pathogenesis (data not shown, significance defined as …

… In order to determine whether the changes in susceptibility seen with age were associated
with changes in lifespans or cell size, we determined the replicative lifespan (RLS) (Figure 6A…

… IMPORTANCE Cryptococcus neoformans and Candida … drugs (10) because it is essential
for fungal virulence (11). This study … to elucidate the implications of EV secretion during aging, …

… glabrata, and Cryptococcus neoformans are pathogenic yeasts … The studies indicate that
aging is relevant for virulence in … effect on life span that was observed by chemical modulation …

… that replicative aging conveys enhanced resilience within the host environment. 78 … To
investigate the effects of replicative aging on gene expression in Cn, we performed 94 …

… plays an important role in virulence and may be a novel … Dcp2, which subsequently modulates
the RCK family protein Vad1 … statistical significance of the difference between the samples. …

… gattii exhibited cell wall damage and reduced virulence, whereas Cda1 defects had no
effect on the … [65], and Hsp70 was recently proved to modulate the interaction between C. …