… TP53 is a well-known tumor suppressor gene and altered by … in colorectal or esophageal
adenocarcinoma, in which TP53 … ICs of microsatellite instability (MSI) type lack TP53 mutation …

… of preneoplastic and associated lesions in mouse stomach. … carcinomas: chromosomal
instability, microsatellite instability (… CRC is mutation in the tumor suppressor gene APC, the Apc- …

… p53 is a tumor suppressor gene and is linked to the … on chromosome 11p15.5, is usually
identified in the stomach and … in DNA repair genes, the presence of microsatellite instability or …

… of molecular alteration in colon polyps and colorectal cancer. … in oncogenes and tumor
suppressor genes drive the … a primary focus of colorectal and esophageal cancer. The classes of …

… then divided GC into MSI, microsatellite stable with epithelial-… , two well-known tumor
suppressor genes displaying roughly 41… A recent study revealed that > 90% esophageal …

… the esophagus, stomach, pancreas, small intestine and colon; the … process through a series
of preneoplastic lesions. In … be the loss of the tumor suppressor gene Apc. The inactivation of …

… -induced neoplasms include epithelial tumors (esophageal … With regards to dysplastic
lesions, microsatellite instability (… the loss of the p53 tumor suppressor gene leads to unchecked …

… by epithelial cells in the stomach, small intestine, colon, and … Mutations in tumor suppressor
genes (TSGs) and oncogenes … OS and disease-free survival (DFS) than microsatellite stable …

… ”: not only molecular -pathologic changes in pre-neoplastic cells but also … The molecular
profile of colon cancers with microsatellite … of p53 tumor suppressor gene and other mutations. …

… The existence of preneoplastic lesions in esophageal NETs (E… , as confirmed by microsatellite
marker analyses, and SCLCs … For instance, mutations in the TP53 tumor suppressor gene …