Lower expression of GBP2 associated with less immune cell infiltration and poor prognosis in skin cutaneous melanoma (SKCM)

S Zhang, K Chen, Z Zhao, X Zhang, L Xu… - … of Immunotherapy, 2022 - journals.lww.com
… of the immune microenvironment, 7 and tumor antigens can … molecular markers of immune
infiltration cells and negatively … modifications, which can be as a crucial epigenetic regulator of …

[HTML][HTML] … profiles differ in responders versus non-responders to anti-PD-1 immune checkpoint inhibitors in patients with advanced and metastatic head and neck …

AM Starzer, G Heller, E Tomasich… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
… genes involved in cancer-related molecular pathways. Over-… potential of durable responses,
immune-related side effects … Due to clinical indications in our patients the first radiological …

[HTML][HTML] Unleashing tumour-dendritic cells to fight cancer by tackling their three A's: abundance, activation and antigen-delivery

A Murgaski, PMR Bardet, SM Arnouk, EJ Clappaert… - Cancers, 2019 - mdpi.com
… ICIs due to an immunosuppressive tumour microenvironmentmetastatic melanoma patients,
of which nine of the treated … induce long-lasting anti-tumour immune responses in patients. …

[HTML][HTML] Response to immune Checkpoint inhibitors is affected by Deregulations in the antigen presentation machinery: A systematic review and meta-analysis

M Rasmussen, JA Durhuus, M Nilbert… - Journal of Clinical …, 2022 - mdpi.com
… (ipilimumab) drugs where molecular investigations including the following … malignant
melanoma and an associated lung metastasis … HLA class I can be epigenetically downregulation …

Prognostic and clinicopathological value of PD-L1 in melanoma: a meta-analysis

J Xu, F Wang, Y Yan, Y Zhang, Y Du, G Sun - The American Journal of the …, 2020 - Elsevier
Immunotherapy is a promising strategy to treat melanoma. … was associated with the poor
clinicopathological characteristics of … As tumor cells and TILs in the tumor microenvironment

Genomic Biomarkers of Response and Resistance to Immune Checkpoint Therapies Across Solid Tumors

D Miao - 2019 - dash.harvard.edu
… mostly within the tumorimmune microenvironment, biomarker … Patients treated with ipilimumab
for metastatic melanoma in … have predictive value for ipilimumab-based therapy. In contrast…

[HTML][HTML] CD8+ cytotoxic and FoxP3+ regulatory T lymphocytes serve as prognostic factors in breast cancer

GL Peng, L Li, YW Guo, P Yu, XJ Yin… - American journal of …, 2019 - ncbi.nlm.nih.gov
associated with adverse outcomes in patients with breast … was associated with the four
molecular subtypes (Table 5). … tumor immune response, breast cancer cells could escape from the …

Moving toward improved immune checkpoint immunotherapy for advanced prostate cancer

MA De Velasco, Y Kura, K Fujita… - International Journal of …, 2024 - Wiley Online Library
… to the arsenal and is being used for patients with melanoma. … , including one patient (6.7%)
with a complete remission, 20% … or without Ipilimumab based on percentage of tumoral CD8 …

[HTML][HTML] Identification of cervical squamous cell carcinoma feature genes and construction of a prognostic model based on immune-related features

C He, L Ren, M Yuan, M Liu, K Liu, X Qian, J Lu - BMC Women's Health, 2022 - Springer
… This study aimed to cluster CSCC samples from a molecular … of these genes in tumor immunity
and cancer development, the … the immune microenvironment is generally associated with …

[图书][B] Imidazoquinoline Prodrugs and Their Potential Applications for Immunotherapy

AJ Burt - 2021 - search.proquest.com
Due to this, there has been rapid development of cancerpatients Coley reports enduring
remission, while in other … by the FDA in 2014 for patients with metastatic melanoma.Since 2014, …