A comparative study of PCS and PAM50 prostate cancer classification schemes
… The PCS and PAM50 classification systems are similar in terms of molecular profiles and …
Many reports have proposed gene expression signatures as a means of tumor classification …
Many reports have proposed gene expression signatures as a means of tumor classification …
Derivation and application of molecular signatures to prostate cancer: opportunities and challenges
D Doultsinos, IG Mills - Cancers, 2021 - mdpi.com
… , a 44 gene expression signature termed the DDR deficiency assay characterized in breast
… a dedicated funding stream to maintain and curate data libraries based on samples routinely …
… a dedicated funding stream to maintain and curate data libraries based on samples routinely …
Identification of a transcriptomic prognostic signature by machine learning using a combination of small cohorts of prostate cancer
… Using a machine learning approach, a total of 14 classifiers were tested with various … and
gene signature to predict BCR. Using a random forest model, we have identified a signature …
gene signature to predict BCR. Using a random forest model, we have identified a signature …
[HTML][HTML] An overview of publicly available patient-centered prostate cancer datasets
T Hulsen - Translational andrology and urology, 2019 - ncbi.nlm.nih.gov
… available or available after signing a research data agreement … These are only the curated
datasets; there are in total 834 … LNCaP prostate cancer cell line and MDA-MB-453 molecular …
datasets; there are in total 834 … LNCaP prostate cancer cell line and MDA-MB-453 molecular …
Reference-free transcriptome exploration reveals novel RNAs for prostate cancer diagnosis
M Pinskaya, Z Saci, M Gallopin, M Gabriel… - Life science …, 2019 - life-science-alliance.org
… signature among putative new lncRNAs using several filters (Fig S3A). Hereafter, we will use
the term signature … To define a molecular signature independent of PSA, we excluded this …
the term signature … To define a molecular signature independent of PSA, we excluded this …
Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer
MP Labrecque, IM Coleman, LG Brown… - The Journal of …, 2019 - Am Soc Clin Investig
… These molecular classifications could potentially guide future … At the transcriptome level,
expression signatures for … We used the curated pathways from within the MSigDBv6.1. Gene …
expression signatures for … We used the curated pathways from within the MSigDBv6.1. Gene …
Therapeutic implications for intrinsic phenotype classification of metastatic castration-resistant prostate cancer
… –resistant prostate cancers (mCRPC) partition into molecular … breast carcinomas using the
PAM50 gene signature. PAM50 … influencing PAM50 heterogeneity, we curated RB1, TP53, …
PAM50 gene signature. PAM50 … influencing PAM50 heterogeneity, we curated RB1, TP53, …
Prostate epithelial genes define therapy-relevant prostate cancer molecular subtype
H Han, HH Lee, K Choi, YJ Moon, JE Heo… - … Cancer and Prostatic …, 2021 - nature.com
… , we used a previously published gene expression signature associated with breast tumor
response … Collectively, we present a novel PCa molecular classification system, connecting the …
response … Collectively, we present a novel PCa molecular classification system, connecting the …
Identification of key regulators in prostate cancer from gene expression datasets of patients
… genes from networks generated using curated list of genes … studies have been limited to the
curated gene list forming the … nature indicating that there is no signature of rich club formation …
curated gene list forming the … nature indicating that there is no signature of rich club formation …
[HTML][HTML] Immunogenomic profiling and classification of prostate cancer based on HIF-1 signaling pathway
J Song, W Chen, G Zhu, W Wang, F Sun… - Frontiers in Oncology, 2020 - frontiersin.org
… The Gene sets based on the c2/c5 curated signatures were downloaded from the Molecular
Signature Database (MSigDB) of Broad Institute. KEGG pathways that were upregulated in …
Signature Database (MSigDB) of Broad Institute. KEGG pathways that were upregulated in …