Phosphatidylinositol synthesis at the endoplasmic reticulum

NJ Blunsom, S Cockcroft - … Acta (BBA)-Molecular and Cell Biology of Lipids, 2020 - Elsevier
Phosphatidylinositol (PI) is a minor phospholipid with a characteristic fatty acid profile; it is …
phospholipase C signalling, where hydrolysis of phosphatidylinositol (4,5) bisphosphate (PI(4,…

Phosphatidylinositol 5 phosphate (Pi5p): From behind the scenes to the front (nuclear) stage

A Poli, AE Zaurito, S Abdul-Hamid, R Fiume… - … Journal of Molecular …, 2019 - mdpi.com
… the role of this mono-phosphoinositide in cell cycles, stress … rare phosphoinositide can
lead to different nuclear outputs. … here we will focus on phosphatidylinositol 5-phosphate (PI5P…

CDP-diacylglycerol synthases (CDS): gateway to phosphatidylinositol and cardiolipin synthesis

NJ Blunsom, S Cockcroft - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Cytidine diphosphate diacylglycerol (CDP-DAG) is a key intermediate in the synthesis of
phosphatidylinositol (PI) and cardiolipin (CL). Both PI and CL have highly specialized roles in …

Defining the subcellular distribution and metabolic channeling of phosphatidylinositol

JG Pemberton, YJ Kim, J Humpolickova… - … of Cell Biology, 2020 - rupress.org
… approach to various organelle membranes in order to validate the PI distributions mapped …
the prominent localization of the BcPI-PLC-based probes, we first tested the localization of the …

Phosphatidylinositol Kinases and Phosphatases in Entamoeba histolytica

K Nakada-Tsukui, N Watanabe, T Maehama… - Frontiers in cellular …, 2019 - frontiersin.org
… There are several enzymes that have the nuclear localization signal: one phosphatidylinositol
phosphate (PIP) kinase, two PI 3-phosphatases, and one PI 5-phosphatase; this suggests …

Human eosinophil lysophospholipase (Charcot-Leyden crystal protein): molecular cloning, expression, and potential functions in asthma

SJ Ackerman, Z Zhou, DG Tenen… - Eosinophils in allergy …, 2019 - taylorfrancis.com
… Role of Ca2+ in phosphatidylinositol response and arachidonic acid release in formylated
tripeptide- or Ca2+ ionophore A23187stimulated guinea pig neutrophils. J Immunol 1983; 130:…

Identification and in silico characterization of a novel point mutation within the phosphatidylinositol glycan anchor biosynthesis class G gene in an Iranian family with …

N Parsamanesh, H Safarpour, S Etesam… - Journal of Molecular …, 2019 - Springer
… Exome sequencing was performed, as well as … this chromosomal location was proposed
as the disorder-causing variant. This Arg658Gln alteration was confirmed by Sanger sequencing

Nuclear phosphatidylinositol 5-phosphatase is essential for allelic exclusion of variant surface glycoprotein genes in trypanosomes

I Cestari, H McLeland-Wieser… - Molecular and Cellular …, 2019 - Taylor & Francis
… We show that nuclear phosphatidylinositol 5-phosphatase (PIP5Pase) interacts with … RAP1
binds PIP5Pase substrate phosphatidylinositol 3,4,5-trisphosphate [PI(3,4,5)P3], and catalytic …

Analysis of the roles of phosphatidylinositol-4,5-bisphosphate and individual subunits in assembly, localization, and function of Saccharomyces cerevisiae target of …

MN Martinez Marshall… - Molecular biology of …, 2019 - Am Soc Cell Biol
… -4,5-bisphosphate and individual subunits in assembly, localization, and function of
Saccharomyces cerevisiae target of rapamycin complex 2 | Molecular Biology of the Cell …

The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis

DM Sørensen, HW Holen, JT Pedersen… - Molecular Biology of …, 2019 - Am Soc Cell Biol
phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis | Molecular
Biology … separated from Spf1p localization, indicating that this phosphoinositide could be a …