… Bitter taste receptors (Tas2rs) initiate a bitter taste signaling involving the activation of … and
taste related G proteins in rat to determine the expression of their mRNAs in the denuded rat …

… Taste receptors are G protein–coupled receptors (GPCRs) … levels through the activation of
phosphodiesterase (PDE) or the … Tas2r31 (known as Tas2r140 in rat), we hypothesized that …

… denatonium acts via G protein-coupled receptors. Tas2R108 … The application of the
phosphodiesterase inhibitor IBMX (100 … Denatonium acts on G protein-coupled taste receptors. (A) …

… taste receptors (T2Rs) are GPCRs involved in detection of bitter compounds by type 2 taste
cells … responses in several cell types. Expression of T2Rs has been demonstrated in immune …

… Bitter taste receptors (TAS2Rs) have been implicated in roles other than … The molecular
biology studies have showed that Tas2r108 and Tas2r139 were expressed in the rat pulmonary …

… Cloning of G protein and phosphodiesterase from rat taste … The Roche Institute of Molecular
Biology has shown that rod … previously identified and cloned from rat taste cells. Neither …

… with genes that encode functional receptors in rats and mice. … The phosphodiesterase
inhibitor zaprinast [2105] has become widely … of bitter taste receptors is not yet established. Bitter …

… mammalian tissues such as hamster, rat, and guinea pig lung [… GRK5 was also cloned from
a taste cell cDNA library [35]. It is … inhibit rod cGMP phosphodiesterase activity [42,43,44]. The …

… taste receptors, the subclass of G protein-coupled receptors … The Gα subunit activates
phosphodiesterases, which reduce … cloned from rat heart, they tested 12 candidate bitter …

… The expression of adenyl cyclases and phosphodiesterases and sweetener-evoked cAMP
… identified Gα subunit in taste cells belonging to the G(t) subfamily of Gα proteins, can couple …