… target, and its involvement in resistance to targeted therapies. Finally, we … using cancer
models that have tested the efficacy of SFKs inhibitors. We hope to shed light on novel strategies …

… microenvironment of these tumors, and the recognition of the molecular mediators of their …
novel therapeutic targets.NET cells overexpress a plethora of proangiogenic molecules …

… of citrate in the regulation of both tumor cells and immune cells, the underlying molecular
mechanisms, and the potential of using citrate as a novel therapeutic agent and a biomarker. …

… strategies is a crucial unmet need for GEP-NENs. … interplay among the TIME, tumor cells,
and the stromal environment. Finally, we summarize novel treatment options related to the TIME …

… TMMs in cancer, specifically focusing on the molecular alterations driving telomere
maintenance in neuroblastoma, before describing potential novel therapeutic strategies to directly …

… Summary of genetic markers in pancreatic neuroendocrine neoplasms. Genetic markers are
presented in green. … Summary of genetic markers in pancreatic neuroendocrine neoplasms. …

… more patients, targeting additional mechanisms of tumor immune evasion will be critical [226…
of novel therapeutic approaches [227]. The development of combinatorial strategies that …

… molecular drivers, a paucity of patient-relevant preclinical models to study biology and test
novel therapeutics… made pertaining to molecular subtyping of small cell lung cancer (SCLC), a …

… the pancreatic head, suspicious for a small insulinoma, but endoscopic ultrasound failed to
localize the tumor… any abnormal uptake concerning for neuroendocrine tumor, and a selective …

… the potential of erastin or RSL3 independently and in combination with standard-of-care
second-generation antiandrogens as novel therapeutic strategies for advanced prostate cancer. …