An update on the regulatory mechanisms of NLRP3 inflammasome activation
… that culminate in NLRP3 inflammasome complex assembly. A better understanding of the
molecular mechanisms underlying NLRP3 inflammasome activation will provide opportunities …
molecular mechanisms underlying NLRP3 inflammasome activation will provide opportunities …
The NLRP3 inflammasome: an overview of mechanisms of activation and regulation
N Kelley, D Jeltema, Y Duan, Y He - International journal of molecular …, 2019 - mdpi.com
… priming signals regulate NLRP3 inflammasome activation through … the mechanism by which
Nek7 regulates NLRP3 activation … molecular mechanism of NLRP3 inflammasome activation …
Nek7 regulates NLRP3 activation … molecular mechanism of NLRP3 inflammasome activation …
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
KV Swanson, M Deng, JPY Ting - Nature Reviews Immunology, 2019 - nature.com
… the molecular, cell biological and biochemical bases of NLRP3 activation and regulation
and … of the molecular mechanisms of NLRP3 inflammasome activation to identify effective …
and … of the molecular mechanisms of NLRP3 inflammasome activation to identify effective …
Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors
Y Yang, H Wang, M Kouadir, H Song, F Shi - Cell death & disease, 2019 - nature.com
… It is well known that Tranilast has anti-inflammatory effects, and it can prevent IgE-induced
histamine secretion from mast cells 107,108 , but the molecular mechanisms are not clearly …
histamine secretion from mast cells 107,108 , but the molecular mechanisms are not clearly …
Advances in the molecular mechanisms of NLRP3 inflammasome activators and inactivators
D Liu, X Zeng, X Li, C Cui, R Hou, Z Guo… - Biochemical …, 2020 - Elsevier
… activation and inactivation of NLRP3 inflammasome. This review summarizes current
understanding of the molecular basis of NLRP3 inflammasome activation … at NLRP3 …
understanding of the molecular basis of NLRP3 inflammasome activation … at NLRP3 …
Modulatory mechanisms of NLRP3: Potential roles in inflammasome activation
Q Ge, X Chen, Y Zhao, H Mu, J Zhang - Life Sciences, 2021 - Elsevier
… regulate NLRP3 expression to provide therapeutic insights for treating inflammasome related
… , positively regulates NLRP3 inflammasome activation through its phosphatase activity [89]. …
… , positively regulates NLRP3 inflammasome activation through its phosphatase activity [89]. …
Inflammasome activation and regulation: toward a better understanding of complex mechanisms
… and molecular mechanisms underlying the regulation of … NLRP3 inflammasome activation
by regulating NLRP3 … -mediated negative regulation of the NLRP3 inflammasome include the …
by regulating NLRP3 … -mediated negative regulation of the NLRP3 inflammasome include the …
Inflammasome activation: from molecular mechanisms to autoinflammation
S Lara‐Reyna, EA Caseley, J Topping… - Clinical & …, 2022 - Wiley Online Library
… In this review, we will explore the molecular processes underlying the activation of several …
steps in inflammasome activation. NLRP3 inflammasome activation involves TLR signalling to …
steps in inflammasome activation. NLRP3 inflammasome activation involves TLR signalling to …
Molecular mechanism for NLRP6 inflammasome assembly and activation
… Because NLRP6 has a PYD, we hypothesized that it might also use a similar assembly
mechanism as AIM2 and NLRP3 inflammasomes through the adaptor ASC. To test this …
mechanism as AIM2 and NLRP3 inflammasomes through the adaptor ASC. To test this …
The NLRP3 inflammasome: activation and regulation
… modifications regulate the NLRP3 inflammasome at both the priming and activation steps. …
binding protein 1 regulates NLRP3 activation through RIPK1-RIPK3-caspase-8 signaling [ …
binding protein 1 regulates NLRP3 activation through RIPK1-RIPK3-caspase-8 signaling [ …
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