… a decrease in luminescence signal for CCR1 in the case of GRK5/6, as expected due to …
In order to uncover the molecular mechanism directing this functional divergence of DARC, we …

… , researchers found that a low white blood cell (WBC) count was predominantly due to … , the
ACKR1 rs2814778 polymorphism, regulating Duffy antigen expression, had a clear influence …

… be the Duffy blood group antigen or that they were closely linked … failed to reveal significant
expression of DARC by endothelial … The molecular basis of this tissue specific expression of …

… This background has inextricably linked Duffy blood group genetics and malaria. Recent
studies now report P. vivax infections in Fy-negative individuals from many malarious African …

… lacking the Duffy antigen on their erythrocytes (Duffy-negative… if increased pvdbp copy
number leads to increased protein … underlying molecular mechanisms remain to be elucidated. …

… vivax malaria in individuals carrying FyA allele due to the significantly reduced binding of …
invasion mechanism [1]. DARC is a single copy gene which encodes Duffy antigen consisting …

… held to explain the molecular basis of Duffy-negative P. vivax … The Duffy protein is a receptor
for chemokines (Duffy antigen … at very low levels, leading to an amount of Duffy protein …

… cause fetal erythrocyte destruction. Alloantibodies against antigens in the Rh, Kell, Kidd,
Duffy, … In summary, antigen loss is a potential mechanism closely linked with AMIS effects in a …

… Duffy antigen is a chemokine receptor that is important in the inflammatory response. Those
who lack this antigen, and type as Duffy … Due to the diverse cellular and tissue expression of …

… messenger response such as calcium release, likely due to a lack of G protein coupling. …
molecular mechanism of this intriguing functional divergence exhibited by the Duffy antigen …