The pathophysiology of the antiphospholipid syndrome: a perspective from the blood coagulation system

R Arreola-Diaz, A Majluf-Cruz… - Clinical and Applied …, 2022 - journals.sagepub.com
antiphospholipid syndrome (… antiphospholipid antibodies such as lupus anticoagulant,
anti-β-2-glycoprotein 1, and/or anticardiolipin antibodies. In the obstetrical APS, antiphospholipid

Mechanisms of immunothrombosis and vasculopathy in antiphospholipid syndrome

JS Knight, Y Kanthi - Seminars in immunopathology, 2022 - Springer
… also key drivers of APS pathophysiology. Thrombotic events in … This review will highlight
known pathogenic factors in APS … a barrier that selectively permits molecular and cellular transit …

New biomarkers for atherothrombosis in antiphospholipid syndrome: genomics and epigenetics approaches

C Lopez-Pedrera, N Barbarroja… - Frontiers in …, 2019 - frontiersin.org
disorder, characterized by pregnancy morbidity and/or a hyper coagulable state involving
the venous or the arterial vasculature and associated with antiphospholipid … of the molecular

Antiphospholipid syndrome: a clinical perspective

Y Zuo, H Shi, C Li, JS Knight - Chinese Medical Journal, 2020 - mednexus.org
… [20,21] As the pathogenesis of APS has been reviewed in … that may advance our understanding
of APS pathogenesis. … inflammatory molecules (intercellular cell adhesion molecule […

[HTML][HTML] Complement in the pathophysiology of the antiphospholipid syndrome

S Chaturvedi, RA Brodsky, KR McCrae - Frontiers in immunology, 2019 - frontiersin.org
… The antiphospholipid syndrome (APS) is characterized by thrombosis and pregnancy
morbidity in the presence of antiphospholipid antibodies (aPL). Complement is a system of …

Management of antiphospholipid syndrome

I Uthman, MHA Noureldine, G Ruiz-Irastorza… - Annals of the …, 2019 - ard.bmj.com
… to the pathogenesis of antiphospholipid syndrome. Anticoagulation remains the cornerstone
in the management of antiphospholipid syndrome; … in antiphospholipid syndrome. …

Antiphospholipid syndrome

LR Sammaritano - Best Practice & Research Clinical Rheumatology, 2020 - Elsevier
Antiphospholipid syndrome is an autoimmune systemic disorder characterized by arterial,
venous, or small vessel thrombosis and/or recurrent early pregnancy loss, fetal loss, or …

[HTML][HTML] Antiphospholipid syndrome: complement activation, complement gene mutations, and therapeutic implications

S Chaturvedi, EM Braunstein, RA Brodsky - Journal of Thrombosis and …, 2021 - Elsevier
Antiphospholipid syndrome (APS) is an acquired thromboinflammatory disorder characterized
by the presence of antiphospholipid … complement in the pathophysiology of thrombosis in …

Cardiac manifestations of antiphospholipid syndrome with focus on its primary form

T Kolitz, S Shiber, I Sharabi, A Winder… - Frontiers in …, 2019 - frontiersin.org
… The antiphospholipid syndrome (APS) is an autoimmune disease characterized by the
presence of antiphospholipid antibodies (aPL) leading to arterial and venous thrombosis and …

Antiphosphatidylserine/prothrombin antibodies: an update on their association with clinical manifestations of antiphospholipid syndrome

M Radin, SG Foddai, I Cecchi, E Rubini… - Thrombosis and …, 2020 - thieme-connect.com
… The site of binding on the prothrombin molecule is still under … recognize different sites of the
prothrombin molecule.[29] So … the phospholipid-binding site of the prothrombin molecule. A …