Dasatinib plus Peg‐Interferon alpha 2b combination in newly diagnosed chronic phase chronic myeloid leukaemia: Results of a multicenter phase 2 study (DASA …

…, F Guilhot, French CML Group (FiLMC) - British Journal of …, 2023 - Wiley Online Library
… real-time quantitative polymerase chain reaction analysis on … for potential competing events
unrelated to CML or therapy. In … Finally, using an initial monitoring of the dose of dasatinib, …

A randomized, phase II trial of adjuvant immunotherapy with durable TKI-free survival in patients with chronic phase CML

JA Webster, TM Robinson, AL Blackford, E Warlick… - Leukemia research, 2021 - Elsevier
… Real-time quantitative polymerase chain reaction (RT-PCR) … ) vaccine and interferon alpha
(IFN) are therapies with immune … Hematologic parameters and chemistries were monitored

Discontinuation of tyrosine kinase inhibitors in patients with chronic myeloid leukemia: a review of the biological factors associated with treatment-free remission

R Stuckey, JF López Rodríguez… - Current Oncology …, 2022 - Springer
… Despite efficient TKI treatment, the persistence of leukemic … from many years ago that
interferon alpha (IFNα) could … useful for the monitoring of residual disease in patients attempting a …

Tyrosine Kinase Inhibitor Discontinuation in Chronic Myeloid Leukemia: Strategies to Optimize Success and New Directions

D Rea, S Fodil, E Lengline, E Raffoux… - Current Hematologic …, 2024 - Springer
interferon alpha [4]. Since then, more potent type I and II ATP-… reverse transcriptase polymerase
chain reaction (RTQ-PCR): … In the TWISTER trial, BCR::ABL1 transcript monitoring in the …

Digital droplet PCR as a predictive tool for successful discontinuation outcome in chronic myeloid leukemia: Is it time to introduce it in the clinical practice?

G Colafigli, E Scalzulli, A Di Prima, S Pepe… - Critical Reviews in …, 2021 - Elsevier
… quantitative polymerase chain reaction (RQ-PCR) has so far been utilized to monitor minimal
… treated with frontline imatinib without previous exposure to interferon-alpha. ddPCR was …

New tool for monitoring molecular response in patients with chronic myeloid leukemia

T Badar, R Luthra, H Kantarjian… - Applied …, 2019 - journals.lww.com
… using polymerase chain reaction-based peripheral blood … polymerase chain reaction
methodologies. We performed the initial analytic performance evaluation of a novel competitive

Chronic myeloid leukaemia: Biology and therapy

Y Wang, Z Liang, RP Gale, H Liao, J Ma, T Gong… - Blood Reviews, 2024 - Elsevier
… of monitoring BCR::ABL1 transcription levels in CML to … cells by qualitative real time polymerase
chain reaction (qRT-PCR). An … Before the era of TKI, combing interferon-alpha with other …

Current status and novel strategy of CML

K Morita, K Sasaki - International journal of hematology, 2021 - Springer
… transcriptase-polymerase chain reaction (RT-PCR) [9,10,11]. … 400 mg daily over
interferon-alpha in combination with … symptoms and signs of chronic toxicity need to be monitored. …

Enabling access to molecular monitoring for chronic myeloid leukemia patients is cost effective in China

VK Maheshwari, C Slader, N Dani, C Gkitzia, Q Yuan… - PLoS …, 2021 - journals.plos.org
monitoring using quantitative polymerase chain reaction (… cost effectiveness of molecular
monitoring in patients with CML… standard CML treatment to no molecular monitoring from a …

Human leukocyte antigen-B phenotype and minimal residual disease in chronic myeloid leukemia patients treated with imatinib: Is there an association?

E Hadad, A Ehsanpour, T Vosoughi… - Clinical Cancer …, 2020 - search.ebscohost.com
… ) in chronic myelogenous leukemia (CML) patients treated … by real‑time polymerase chain
reaction technique. Results: No … of the drugs used to treat cancer such as interferonalpha (…