… single domain monothiol glutaredoxin 5, the chloroplastic single domain monothiol
glutaredoxin S14 and S16, the nuclear/cytosolic multi-domain monothiol glutaredoxin 3, and the …

… for their various functions under … domain enzymes or multi-domain enzymes that contain
an N-terminal thioredoxin-like domain and between one and three C-terminal monothiol …

… and role of the monothiol Grxs in redox chemistry remains controversial due to several …
-cysteine domain or the so-called “hybrid Trx-Grx-domain” [4]. Humans utilize both mono-cysteine …

… with a metal-binding domain as a protein disulfide substrate … monothiol glutaredoxins can
support the efficient reduction of … functions of monothiol and dithiol class I glutaredoxins in …

… /clustering of various redoxins from all domains of life based on … The members of a second
subclass of the Grxs (monothiol … best partially, reflect the various functions of the proteins. As …

… and the N-terminal domain of glutathione … function, glutaredoxin can also denitrosylate
proteins-SNO, and the mechanism of denitrosylation is expected to be analogous to the monothiol …

… number of domains, 1CGrx proteins can be classified into two groups: (i… functions to Grx5,
we employed the Lin1CGrx-complemented Grx5 yeast mutants and determined the rate of O 2 …

… To test the role of Grx3 in virulence in vivo, we utilized two murine models of candidiasis.
In a disseminated model of candidiasis, mice infected with wild-type cells did not survive past …

… cytosolic monothiol glutaredoxin GrxD plays an essential role … of the CGFS motif and two
glutathione residues, which leads … cysteine residue in the Trx domain are framed. Identical …

… dual function of peroxiredoxin as peroxidase and H 2 O 2 -… GSH-mixed disulfides is catalyzed
by glutaredoxin (Grx). GSH … disulfide, which, in the monothiol mechanism, is resolved by a …