… In recent years, more large-scale longitudinal cohort studies and cumulative evidence …
We excluded studies which did not specify the drug of use and studies focusing on only HIV-…

… We included cohort studies of people who used … mortality among cohorts was associated
with the prevalence of injecting drug use, HIV infection, and HCV infection within study …

… Among the cohort studies, the rate of all-cause mortality … of methadone treatment, rates of
all-cause mortality and drug-related … with ongoing studies of mortality among people with opioid …

… have poor health outcomes, with cohort studies finding mortality rates of up to 15 times the
… or with distinct drug use patterns, while others duplicated samples from other studies, and …

… study defined regular cocaine use as using cocaine at least monthly during the year prior to
when the study … all-cause mortality among cocaine users compared with cocaine nonusers. …

… , 21 424 461 cases of illicit drug use, 19 433 038 cases of … to annual mortality, building on
previous research that has … well as elevated risk for early mortality among those exposed to CA. …

… mortality hazard ratios or mortality rate ratios were extracted and pooled with SMRs.
Random-effects meta-analysis … Studies were restricted to clinical cohort studies written in English. …

… , drug related (problematic drug use or accidental drug poisoning… crude mortality rates, we
summed the number of deaths by … that confirm results of previous systematic reviews and meta-…

… large randomised controlled trials investigating the effect of lifestyle intervention on mortality
among individuals with cancer or CVD, evidence from high-quality cohort studies is urgently …

… were population-based cohort studies of all patients with identified COVID-19 exploring the
… and Relevance In this systematic review and meta-analysis of 16 observational studies in 7 …