[HTML][HTML] Structural insights into the lipid A transport pathway in MsbA

PS Padayatti, SC Lee, RL Stanfield, PC Wen… - Structure, 2019 - cell.com
lipid A are revealed not only inside MsbA, but also in a cleft on MsbA's outer surface at
the periplasmic face of the bilayer, which we hypothesize as a possible post-transport lipid A …

Cardiolipin aids in lipopolysaccharide transport to the gram-negative outer membrane

MV Douglass, F Cléon… - Proceedings of the …, 2021 - National Acad Sciences
… A–core oligosaccharide from the inner leaflet to the periplasmic … increased GPLs presented
at the bacterial surface (27). One … PagP-acylated lipid A in our msbA suppressors, suggesting …

The lipid A 1-phosphatase, LpxE, functionally connects multiple layers of bacterial envelope biogenesis

J Zhao, J An, D Hwang, Q Wu, S Wang, RA Gillespie… - Mbio, 2019 - Am Soc Microbiol
… -based Kdo 2 -lipid IV A 1-dephosphorylation assay of the … helix lying at the periplasmic
surface of the inner membrane and … Apart from α2, which originates from the periplasmic surface

[HTML][HTML] Remodelling of the Gram-negative bacterial Kdo2-lipid A and its functional implications

MA Valvano - Microbiology, 2022 - microbiologyresearch.org
… inner membrane by the ABC transporter MsbA [2]. The Kdo2-… a donor, modifying lipid A on
the periplasmic side of the inner … lipid for peptidoglycan, O antigen and other bacterial surface

Identification of a phosphoethanolamine transferase for lipid A modification in Vibrio parahaemolyticus

X Tan, J Qiao, Q Zhou, D Huang, H Li, J Wang, X Wang - Food Control, 2021 - Elsevier
… parahaemolyticus invading the macrophage cells; on the other hand, modification of PEA
of lipid A significantly decreases the negative charge on the surface of V. parahaemolyticus, …

[HTML][HTML] Biosynthesis of the Inner Core of Bordetella pertussis Lipopolysaccharides: Effect of Mutations on LPS Structure, Cell Division, and Toll-like Receptor 4 …

J Pérez-Ortega, R van Boxtel, M Plisnier… - International Journal of …, 2023 - mdpi.com
lipid A (Figure 1). These phosphatases are integral inner-membrane proteins and present
their active site towards the periplasm. … the phosphate at position 1 of heterologous lipid A [12]. …

Metabolic engineering of Escherichia coli to produce a monophosphoryl lipid A adjuvant

Y Ji, J An, D Hwang, SM Lim, C Lee, J Zhao… - Metabolic …, 2020 - Elsevier
… Total lipids were dissolved in chloroform and methanol at a ratio of 4:1 (v/v). The resuspended
lipid samples were loaded on a matrix consisting of 10 mg/mL 2,5-dihydroxybenzoic acid …

Engineering Escherichia coli MG1655 to Efficiently Produce 3-Deacyl-4′-monophosphoryl Lipid A

Z Wang, A Zhao, J Qiao, J Yu, F He, Y Bi… - Journal of Agricultural …, 2023 - ACS Publications
… Among these seven proteins, MlaC, a soluble periplasmic protein, can transfer … Fimbriae
are macromolecular protein polymers that grow on the surface of cells and participate in a …

Metabolic engineering of Escherichia coli to efficiently produce 3-deacyl-2-acyloxyacyl-4′-monophosphoryl-lipid A

A Zhao, Z Wang, J Yu, F He, Y Bi, X Wang - Systems Microbiology and …, 2024 - Springer
… -negative bacteria, is composed of o-antigen, core oligosaccharide, and lipid A. LPS cover
about 75% of the cell surface and act as a stable cell structure and membrane wall barrier [1]. …

[HTML][HTML] Involvement of hpap2 and dgkA Genes in Colistin Resistance Mediated by mcr Determinants

A Gallardo, M Ugarte-Ruiz, M Hernández… - Antibiotics, 2020 - mdpi.com
… oriented to the bacterial periplasm [1]. In … surface [3], were found negatively regulated by
the expression of mcr genes (Figure 5), including those for reducing the negative charge of lipid