Cytomembrane trafficking pathways of Connexin 26, 30, and 43

YJ Zong, XZ Liu, L Tu, Y Sun - International Journal of Molecular Sciences, 2023 - mdpi.com
gap junction formation, ultimately leading to connexin … for connexin 43, connexins 30
and 26, mutations affecting … and Cx30 assemble into two types of gap junctions that form a …

Cytomembrane Trafficking Pathways of Connexin 26, 30 and 43: Recent Updates

YJ Zong, X Liu, L Tu, Y Sun - 2023 - preprints.org
gap junction formation, ultimately leading to connexin … for connexin 43, connexins 30
and 26, mutations affecting … and Cx30 assemble into two types of gap junctions that form a …

Actin-independent trafficking of cochlear connexin 26 to non-lipid raft gap junction plaques

J Defourny, N Thelen, M Thiry - Hearing Research, 2019 - Elsevier
… We observed that Cx26 assembly occurs in non-lipid raft … that cochlear Cx26 gap junction
assembly requires microtubules … into Cx26 trafficking pathway and gap junction assembly in …

[HTML][HTML] Cochlear connexin 30 homomeric and heteromeric channels exhibit distinct assembly mechanisms

J Defourny, N Thelen, M Thiry - Mechanisms of Development, 2019 - Elsevier
… of the mutations in GJB2 and GJB6, which encode connexins 26 … heteromeric gap junctions
exhibit distinct assembly mechanisms in … of gap junctions involving connexin trafficking and …

[HTML][HTML] Recent advances in connexin gap junction biology

PD Lampe, DW Laird - Faculty Reviews, 2022 - ncbi.nlm.nih.gov
… involved in protein trafficking, connexin turnover, connexin assembly, connexin post-… at
the periphery of the gap junction regulating gap junction turnover 43 in a manner perhaps …

Connexin and gap junctions: perspectives from biology to nanotechnology based therapeutics

S Jindal, S Chockalingam, SS Ghosh… - Translational …, 2021 - Elsevier
assemble in a head-to-head fashion to form the gap junction. … via gap junctions, in
response to a signaling pathway. A … Some molecules comprising the intercellular traffic confer …

Gap junction-dependent and-independent functions of Connexin43 in biology

Y Zhu - Biology, 2022 - mdpi.com
… the full assembly of gap junction connexons, composed of … at multiple sites on its C-terminal
tail to regulate its traffickingmultiple bands below the predicted molecular weight of 43 kD […

[HTML][HTML] Connexins and the epithelial tissue barrier: a focus on connexin 26

L Garcia-Vega, EM O'Shaughnessy, A Albuloushi… - Biology, 2021 - mdpi.com
… the tight junction network [20]. Gap Junction assembly depends on the oligomerisation of …
follow an alternative Golgi-independent trafficking pathway, possibly providing a means for …

Mechanisms of connexin regulating peptides

DR King, MW Sedovy, X Leng, J Xue… - International Journal of …, 2021 - mdpi.com
Gap junctions (GJ) and connexins play integral roles in … within the cell to facilitate protein
trafficking to the plasma membrane, … Both 37,43 Gap27 and 32 Gap24 can reversibly inhibit …

Tricellular adherens junctions provide a cell surface delivery platform for connexin 26/30 oligomers in the cochlea

J Defourny, M Thiry - Hearing Research, 2021 - Elsevier
… remain about connexin trafficking and gap junction biogenesis. Here … role for tricellular
junctions in the trafficking and assembly of … Along the gap junction biogenesis pathway, connexin