The role of polyamine metabolism in cellular function and physiology
RS Schibalski, AS Shulha, BP Tsao… - … of Physiology-Cell …, 2024 - journals.physiology.org
… Polyamines are molecules with multiple amino groups that … be a compensatory mechanism
to maintain 250 polyamine levels … During cardiac hypertrophy, TRPV1 is elevated and 459 …
to maintain 250 polyamine levels … During cardiac hypertrophy, TRPV1 is elevated and 459 …
[HTML][HTML] Polyamine homeostasis in development and disease
S Nakanishi, JL Cleveland - Medical Sciences, 2021 - mdpi.com
… SPD delays cardiac aging by reducing hypertrophy and improving … Interestingly, ASS1 loss
is associated with compensatory … We acknowledge the many outstanding scientists that have …
is associated with compensatory … We acknowledge the many outstanding scientists that have …
[HTML][HTML] Dynamic mitochondrial proteome under polyamines treatment in cardiac aging
H Zhang, M Yan, T Liu, P Wei, N Chai, L Li… - Frontiers in Cell and …, 2022 - frontiersin.org
… Polyamines play multiple roles in the cellular process, such as stabilizing and remodeling
chromosomes, stimulating cell proliferation, and protecting cells under different types of stress (…
chromosomes, stimulating cell proliferation, and protecting cells under different types of stress (…
[HTML][HTML] Right ventricle remodeling metabolic signature in experimental pulmonary hypertension models of chronic hypoxia and monocrotaline exposure
T Hautbergue, F Antigny, A Boët, F Haddad, B Masson… - Cells, 2021 - mdpi.com
… Some compensatory reactions are probably promoted to slow down … polyamines are involved
in the development of cardiac hypertrophy and that cardiac injury is partly offset by several …
in the development of cardiac hypertrophy and that cardiac injury is partly offset by several …
[图书][B] Understanding the evidence-based Role played by Polyamines in Vascular Pathophysiology in animal models of (re) stenosis at molecular level.
H Saboowala - 2020 - books.google.com
… are produced by an intracellular highly regulated pathway or … 1 below) through the addition
of one and two aminopropyl … to compensatory mechanisms leading to homeostasis of cellular …
of one and two aminopropyl … to compensatory mechanisms leading to homeostasis of cellular …
Angiocrine polyamine production regulates adiposity
E Monelli, P Villacampa, A Zabala-Letona… - Nature …, 2022 - nature.com
… However, we observed vascular hyperplasia in the Pten iΔEC WAT, … may be important in
many other biological contexts. … Participants of the study did not receive any compensation. …
many other biological contexts. … Participants of the study did not receive any compensation. …
ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport
B Liu, M Azfar, E Legchenko, JA West… - Cardiovascular …, 2024 - academic.oup.com
… by ATP13A3 deficiency, suggesting a lack of compensation by these related proteins. We
found … This probably explains why multiple endogenous polyamine species are simultaneously …
found … This probably explains why multiple endogenous polyamine species are simultaneously …
Polyamine Biosynthetic Metabolic Dysregulation: Targeting and the Adaptive Response
S Rosario - 2020 - search.proquest.com
… who will be poised to benefit most from polyamine-targeted therapies……………………………
two have truly helped to guide me in every aspect of my life and I am looking forward to many …
two have truly helped to guide me in every aspect of my life and I am looking forward to many …
[HTML][HTML] Mechanism of histone deacetylases in cardiac hypertrophy and its therapeutic inhibitors
Y Han, J Nie, DW Wang, L Ni - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
… to multiple cardiac diseases, especially in cardiac hypertrophy. … is generally considered to
be a compensatory effect that … HDAC10 has been identified as a polyamine deacetylase, with …
be a compensatory effect that … HDAC10 has been identified as a polyamine deacetylase, with …
[HTML][HTML] Glutaminolysis: A driver of vascular and cardiac remodeling in pulmonary arterial hypertension
… metal homeostasis dysregulation, compensatory anaplerosis, … in the heart was observed in
right ventricular hypertrophy in … that involve the control of several downstream characteristics …
right ventricular hypertrophy in … that involve the control of several downstream characteristics …