The role of sex and pregnancy in multiple sclerosis: what do we know and what should we do?

PA McCombe - Expert Review of Neurotherapeutics, 2022 - Taylor & Francis
… measures that address the modifiable risk factors for MS and ensure … This effect could be
related to the ‘MS prodrome’- where … Pathways that showed alterations in methylation in parous …

PPMS onset upon adalimumab treatment extends the spectrum of anti-TNF-α therapy-associated demyelinating disorders

S Engel, F Luessi, A Mueller… - Therapeutic …, 2020 - journals.sagepub.com
… The patient had no family history of multiple sclerosis or … clinical manifestation, as a prodrome
of MS diseases since around … interpretation of TNF-triggered pathways. There are also two …

[HTML][HTML] Endogenous retroviruses in multiple sclerosis: a network-based etiopathogenic model

S Censi, RM Costantini, A Granzotto… - Ageing Research …, 2024 - Elsevier
… etiopathological model for multiple sclerosis pathogenesis and … and environmental factors
contributes to multiple sclerosis. We … anti-retroviral therapy in multiple sclerosis as a disease-…

Air pollution and multiple sclerosis risk

G Giovannoni, CH Hawkes… - Multiple Sclerosis …, 2021 - msard-journal.com
… In conclusion, it seems that air pollution is a risk factor for developing MS. Whether the effects
of air pollution are via direct effects on the immune system as a result of lung inflammation …

Socioeconomic factors in multiple sclerosis

HØ Flemmen - 2023 - duo.uio.no
… in prevalence and incidence of multiple sclerosis (MS) in … to be explained by possible
risk factors like latitude, exposure … in the section of MS prodromes, please see section 3.6.1.2. …

The emerging role of lncRNAs in multiple sclerosis

S Ghaderian, N Shomali, S Behravesh… - Journal of …, 2020 - Elsevier
… and no protein-coding potential. Currently, pieces of evidence have demonstrated that
lncRNAs have fundamental actions in multiple cellular pathways, including immune system …

Longitudinal prevalence and determinants of pain in multiple sclerosis: results from the German National Multiple Sclerosis Cohort study

H Heitmann, B Haller, L Tiemann, M Mühlau… - Pain, 2020 - journals.lww.com
… has been attributed to demyelinating lesions in somatosensory pathways 22,33 such as the
… in early MS 14 and even as prodromal symptoms years before diagnosis. Because fatigue …

Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis

K Bjornevik, M Cortese, BC Healy, J Kuhle, MJ Mina… - Science, 2022 - science.org
… (1) present data that support a causal relationship between EBV infection and MS. Although
EBV infection was earlier identified an acknowledged risk factor for MS, this investigation …

Cumulative roles for Epstein-Barr virus, human endogenous retroviruses, and human herpes virus-6 in driving an inflammatory cascade underlying MS pathogenesis

UC Meier, RC Cipian, A Karimi, R Ramasamy… - Frontiers in …, 2021 - frontiersin.org
… an important role in signaling pathways of multiple Toll-like … ) is the strongest genetic risk
factor for multiple sclerosis (187). … neuritis, a disease frequently prodromic to MS, makes this …

[HTML][HTML] Identifying the culprits in neurological autoimmune diseases

Y Acosta-Ampudia, DM Monsalve… - Journal of Translational …, 2019 - Elsevier
Multiple sclerosis (MS) is the most common NAD with a prevalence of 30.1 cases per … [29],
identified HLA-DRB1*0701 as a novel risk factor in individuals with evidence of recent …