Multichannel bioactive silk nanofiber conduits direct and enhance axonal regeneration after spinal cord injury
R You, Q Zhang, X Li, S Yan, Z Luo… - … Biomaterials Science & …, 2020 - ACS Publications
… conduits with aligned microchannels have been frequently used as implantable scaffolds
for nerve regeneration by attenuating disordered neurite outgrowth. The implantation of …
for nerve regeneration by attenuating disordered neurite outgrowth. The implantation of …
Devising micro/nano-architectures in multi-channel nerve conduits towards a pro-regenerative matrix for the repair of spinal cord injury
X Sun, Y Bai, H Zhai, S Liu, C Zhang, Y Xu, J Zou… - Acta biomaterialia, 2019 - Elsevier
… Consequently, such implanted scaffolds will promote … neurons, thus enhance the inner
regeneration capability of spinal cord. … used as implantable scaffolds for nerve regeneration, in …
regeneration capability of spinal cord. … used as implantable scaffolds for nerve regeneration, in …
Neurotrophin-3-loaded multichannel nanofibrous scaffolds promoted anti-inflammation, neuronal differentiation, and functional recovery after spinal cord injury
X Sun, C Zhang, J Xu, H Zhai, S Liu, Y Xu… - ACS Biomaterials …, 2020 - ACS Publications
… for promoting neuronal differentiation of the recruited NSCs and axonal regeneration. … , not
only served as the guidance for axonal regeneration and outgrowth, but also their nanofibrous …
only served as the guidance for axonal regeneration and outgrowth, but also their nanofibrous …
Polymer scaffolds facilitate spinal cord injury repair
Q Zhang, B Shi, J Ding, L Yan, JP Thawani, C Fu… - Acta biomaterialia, 2019 - Elsevier
… An effective treatment for SCI would not only reduce fractured elements and isolate developing
local glial scars to promote axonal regeneration but also ameliorate secondary effects, …
local glial scars to promote axonal regeneration but also ameliorate secondary effects, …
[HTML][HTML] Newly regenerated axons via scaffolds promote sub-lesional reorganization and motor recovery with epidural electrical stimulation
AM Siddiqui, R Islam, CA Cuellar… - NPJ Regenerative …, 2021 - nature.com
… the lumbroscaral spinal cord could promote axon regeneration … with complete spinal
transection, and with scaffold placement … connectivity via newly regenerating across injury fibers in …
transection, and with scaffold placement … connectivity via newly regenerating across injury fibers in …
Defining spatial relationships between spinal cord axons and blood vessels in hydrogel scaffolds
AM Siddiqui, D Oswald… - … Engineering Part A, 2021 - liebertpub.com
… support of axonal regeneration. This result supports our previous observations that improved
… Matrigel scaffolds minimally supported axonal regeneration at an efficiency of less than 20…
… Matrigel scaffolds minimally supported axonal regeneration at an efficiency of less than 20…
[HTML][HTML] A bionic multichannel nanofiber conduit carrying Tubastatin A for repairing injured spinal cord
S Liao, Y Liu, Y Kong, H Shi, B Xu, B Tang, C Li… - Materials Today Bio, 2022 - Elsevier
… as promoting axonal regeneration during spinal cord injury … and multiple-channel bioactive
silk nanofiber catheter scaffold … promoted spinal cord repair and nerve regeneration, which …
silk nanofiber catheter scaffold … promoted spinal cord repair and nerve regeneration, which …
[HTML][HTML] Multichannel bridges and NSC synergize to enhance axon regeneration, myelination, synaptic reconnection, and recovery after SCI
U Nekanti, PS Sakthivel, A Zahedi… - npj Regenerative …, 2024 - nature.com
… In vitro, hNSC culture on a PLG scaffold increased … along regenerating axons and integrate
into the host spinal cord as … along axons, regenerating into a biomaterial scaffold, and …
into the host spinal cord as … along axons, regenerating into a biomaterial scaffold, and …
Design of hydrogel-based scaffolds for the treatment of spinal cord injuries
N Ghane, MH Beigi, S Labbaf… - Journal of Materials …, 2020 - pubs.rsc.org
… To design a successful engineered SC scaffold as a structural, mechanical and trophic
support to bridge the lesion cavity and stimulate the axonal regrowth, essential parameters …
support to bridge the lesion cavity and stimulate the axonal regrowth, essential parameters …
Fabrication of multi-channel nerve guidance conduits containing schwann cells based on multi-material 3D bioprinting
L Zhang, H Zhang, H Wang, K Guo, H Zhu… - 3D Printing and …, 2023 - liebertpub.com
… The effect of MNGCs and SCs on axon regeneration was confirmed by vivo experiments in
adult … We think that the study of viability is enough to support the fabrication of nerve conduit …
adult … We think that the study of viability is enough to support the fabrication of nerve conduit …