… collagen [6], that can affect the kidney resident cells to a different extent, leading to increased
… In experimental FSGS induced by adriamycin in mice, ET-1 produced by podocytes …

… cause autosomal recessive polycystic kidney disease (ARPKD). … contractility triggered by
integrin-mediated adhesion … of siRNA-silenced murine IMCD cells in a different experimental …

… not only involve integrin-mediated activation of intracellular … These cystic kidneys have
elevated levels of phosphorylated … overexpression of mouse periostin in renal collecting ducts (…

… Itgb1 mutant kidneys displayed extensive collagen deposition in … Integrin-mediated adhesion
to the ECM protects cells from … has been described in the collecting ducts of a mouse model …

… called integrins and integrin-mediated adhesions serve as … to increased collagen I deposition
in the Cx43 +/− mouse [37], … HK2 cells are a clonal proximal tubular epithelial cell line …

… and SHC (Src homology and collagen), which are recruited to the C-… and regulator of
integrin-mediated attachment signaling to the … Interestingly, in both human and mouse kidneys, …

… in regulating integrin-mediated processes such as cell adhesion, … ILK in PBMCs and the
expression of collagen I (Fig. 4ab), … increased under hypertonicity in KC3AC1 cells from mouse …

… An investigation of mouse kidney cell lines cultivated in arginine-replete … Briefly, the T25
flask was coated with Bovine Collagen type I … The cells were grown according to the procedure …

… interstitial collagen deposition (blue) in kidneys was increased by … and PTEN in renal fibrosis
model in mice. A, UUO-induced … with endocytic defect inhibit integrin-mediated pFAK-Y397, …

… proteins such as collagen, proteoglycans, focal adhesion protein tensin, … to cysts and
renal failure in mice [32]. As above, integrins … Thus, PC1 may act as an inhibitor of integrin-mediated …