… (7) found that miscibility is a critical factor for ASDs and described phase separation induced
via the route during ASD formation and caused by water absorption or due to high relative …

… Residual solvent can affect the API solubility in the polymer, molecular … water was
simultaneously fitted to the solubility of crystalline and amorphous RIT in water and the water …

… vials and stored in desiccators at 25 C in order to prevent moisture absorption prior testing.
… ), it is the presence of moisture water and its effect on the physicochemical properties of the …

… -off-the-cliff” effect due to the dramatic impact observed during in vitro dissolution. Han …
sorption experiments using ASD powders (Table 4). The water content required to induce phase …

… As soon as the surface of an ASD encounters water, several interplay processes, including
water sorption, phase separation, crystallization, and the viscosity of the formed (gel) layer, …

… at 25 C and 0.1 MPa depicting the pathways of water sorption and amorphous phase
separation in the ASD with (a) 20 wt% DL and (b) 25 wt% DL at 94% RH. All compositions are …

… separations of ASD samples at low temperatures and drug loadings; (2) reducing the impact
… for six hours were deemed sufficient for the water absorption (Supplementary Materials C), …

… of solid dispersions are so-called ‘amorphous solid dispersions’ (… among all components
mutually affect each other differently. An … separation on the CBZ CDF and water sorption was …

… affect drug release from ternary amorphous solid dispersions (… These surfactants altered
phase separation kinetics and … following water sorption from the vapor phase [39], but phase …

… The water vapor sorption of cinnarizine ternary SDs under 75% and 93% RH at … amorphous
solids absorb water vapor into bulk, and the water molecules interact with amorphous solids …