[HTML][HTML] Investigating molecular interactions between Kaiso and nuclear co-repressor using molecular simulations

B Thapa, NP Adhikari - AIP Advances, 2024 - pubs.aip.org
… (ZF) protein Kaiso mediates the transcription repression by … As a methyl CpG binding protein
(MBP), it recognizes the … its N-terminal POZ/BTB domain in a methylation-dependent manner…

Molecular Interactions of Zinc Finger Protein Kaiso with Hemimethylated DNA

B Thapa, NP Adhikari - Journal of Nepal Physical Society, 2023 - nepjol.info
… finger protein Kaiso, bind with methylated DNA and mediate … sequences that mediate
transcription repression indirectly. … Kaiso contributes to DNA methylation-dependent silencing of …

Proteins That Read DNA Methylation

K Liu, T Shimbo, X Song, PA Wade, J Min - DNA Methyltransferases-Role …, 2022 - Springer
… , the recruitment of the N-CoR complex mediated by Kaiso is proposed as a potential
mechanism of DNA methylation-dependent gene repression. However, Kaiso is also known to …

TRIM28 regulates transcriptional activity of methyl-DNA binding protein Kaiso by SUMOylation

Y Lobanova, G Filonova, D Kaplun, N Zhigalova… - Biochimie, 2023 - Elsevier
… enhances SUMOylation of Kaiso leading to a decreased methyl-dependent repression
ability. TRIM28 is a scaffold protein that regulates … Methylation-dependent repression assay …

A 5′-flanking C/G pair at the core region enhances the recognition and binding of Kaiso to methylated DNA

B Thapa, NP Adhikari, PB Tiwari… - Journal of Chemical …, 2022 - ACS Publications
Methyl CpG binding proteins (MBPs) are transcription factors that recognize the … , Kaiso
mediates the silencing of the tumor suppressor genes in a DNA methylation-dependent manner. (…

Proteins That Read DNA Methylation 11

K Liu, T Shimbo, X Song, PA Wade, J Min - DNA Methyltransferases-Role and … - Springer
N-CoR complex mediated by Kaiso is proposed as a potential mechanism of DNA
methylation-dependent gene repression. … repression through a methyl CpG binding protein Kaiso. …

[HTML][HTML] DNA methylation readers and cancer: mechanistic and therapeutic applications

N Mahmood, SA Rabbani - Frontiers in oncology, 2019 - frontiersin.org
… on how SETDB2 mediates gene repression is still not clear (… (N-CoR) to both methylated
and unmethylated regions on the … For example, Kaiso can cause transcriptional repression of …

ZBTB33 (Kaiso) methylated binding sites are associated with primed heterochromatin

QXX Lin, K Rebbani, S Jha, T Benoukraf - BioRxiv, 2019 - biorxiv.org
repression of miR-31 appears to be methylation dependent, … These events might be mediated
by proteins such as ZBTB33… co-occupancy of N-coR and ZBTB33 across methylated DNA. …

[HTML][HTML] Temporal and differential regulation of KAISO-controlled transcription by phosphorylated and acetylated p53 highlights a crucial regulatory role of apoptosis

SH Choi, DI Koh, SY Cho, MK Kim, KS Kim… - Journal of Biological …, 2019 - ASBMB
… its p53RE1 or p53RE3 sites during early DDR. p53RE1 uniquely contained three p53-binding
half… During the later DDR phase, a KAISO-mediated acetylated p53 form (represented by a …

[HTML][HTML] Regulation of Cathepsin E gene expression by the transcription factor Kaiso in MRL/lpr mice derived CD4+ T cells

S Hiramatsu, KS Watanabe, S Zeggar, Y Asano… - Scientific reports, 2019 - nature.com
… of antigenic peptides during MHC class II-mediated antigen … and Thyroid hormone
receptors)/N-CoR (Nuclear hormone receptor Co-… repression activity of Kaiso, we subcloned the …