… condition characterized by a heterogeneous spectrum of clinical … non-erosive reflux disease
(NERD) and a different treatment … MNBI values were lower in NERD and in normal RI-NOS (…

… the complexities of GERD spectrum, including nonerosive reflux disease (NERD), reflux
hyper… NERD: an umbrella term including heterogeneous subpopulations. Nat Rev Gastroenterol …

… However, in the years that followed, a subpopulation of … became a more heterogeneous
disorder, a concept that was … in the management of NERD and acid reflux hypersensitivity, …

… maintain the umbrella concept of different subpopulations of NERD and, therefore, GERD. …
their pathophysiological heterogeneity [20,57]. If we can easily anticipate that NERD patients …

… us to separate true NERD from esophageal functional disorders … to the subpopulation with
non-erosive reflux disease (NERD) … that patients with NERD are greatly heterogeneous from a …

… ) contains a broad spectrum of heterogeneous disorders, and a … effectively differentiates
true NERD, reflux hypersensitivity, … True NERD can be diagnosed if acid reflux is documented …

… non-erosive reflux disease (NERD), who nowadays represent … that NERD has to be
considered as an umbrella term … subsets the heterogeneous population of patients with NERD […

… that the NERD population is markedly heterogeneous and … ] : (a) patients with true NERD
with an excess of acid burden … an umbrella term encompassing various subpopulations with …

… al., the common practice of identifying “NERD” patients solely on the basis of typical symptoms
and an absence of reflux esophagitis selects for a heterogeneous patient group ( 35 ), of …

… GERD is heterogeneous in terms of varied … NERD toward metaplasia (Barrett’s esophagus)
and neoplasia (esophageal adenocarcinoma). Currently, GERD is used as an umbrella term …