The NF-κB signaling pathway, the microbiota, and gastrointestinal tumorigenesis: recent advances

C Peng, Y Ouyang, N Lu, N Li - Frontiers in Immunology, 2020 - frontiersin.org
cellular proliferation and apoptosis by targeting Bcl2, IAPs, and cyclins. In addition, NF-κB is
essential for the induction … fragilis, intestinal epithelial cells employ several receptors such as …

Autophagy and Apoptosis in Inflammatory Bowel Disease

E Kouroumalis, I Tsomidis, A Voumvouraki - Gastroenterology Insights, 2023 - mdpi.com
… in several functions of intestinal epithelial cells (IECs) and goblet cells, … NF-κB-mediated
survival responses via the ablation of NEMO (NF-κB essential modulator) induced IEC apoptosis

Helicobacter pylori-induced NF-κB: trailblazer for gastric pathophysiology

G Maubach, M Vieth, F Boccellato… - Trends in Molecular …, 2022 - cell.com
apoptotic cell death could lead to mutations and malignant transformation of gastric epithelial
cells … an increase in proliferation, invasion, and the migratory phenotype of epithelial cells. …

The multiple roles of the IAP super-family in cancer

S Kumar, C Fairmichael, DB Longley… - Pharmacology & …, 2020 - Elsevier
Apoptosis proteins (IAPs) are a family of proteins that are mainly known for their anti-apoptotic
revealed that they have extensive roles in governing numerous other cellular processes. …

Cell death in the gut epithelium and implications for chronic inflammation

JV Patankar, C Becker - Nature reviews Gastroenterology & hepatology, 2020 - nature.com
apoptosis 65 . Another study also found that during intestinal injury RIPK3 regulated NF-κB-mediated
inhibitor of apoptosis proteins (IAPs), ultimately leading to apoptotic cell death 67 . …

Function of A20 in the regulation of Helicobacter pylori-induced alternative NK-[kappa] B and caspase-8-dependent apoptotic cell death

MCC Lim - 2022 - repo.bibliothek.uni-halle.de
… of anti-apoptotic genes such as baculoviral IAP repeat-containing 2 (BIRC2), BIRC3 and
B-… Increased gastric epithelial cell apoptosis correlated with the colonisation with CagA-positive …

Matrix Metalloproteinase-9 (MMP-9) induced disruption of intestinal epithelial tight junction barrier is mediated by NF-κB activation

R Al-Sadi, J Engers, M Haque, S King, D Al-Omari… - PLoS …, 2021 - journals.plos.org
… via the NF-κB -mediatedcells from death by inducing expression of anti-apoptotic proteins,
including Bcl-x L , FLICE-like inhibitory protein, and members of the inhibitor of apoptosis (IAP

H. pylori infection confers resistance to apoptosis via Brd4-dependent BIRC3 eRNA synthesis

Y Chen, D Sheppard, X Dong, X Hu, M Chen… - Cell Death & …, 2020 - nature.com
expression and activity of IAPs contributes to the apoptosis … infection on apoptosis resistance
in gastric epithelial cells, we … -κB, to suppress NF-κB-mediated anti-apoptotic effect 45 . H. …

The balance of TNF mediated pathways regulates inflammatory cell death signaling in healthy and diseased tissues

JD Webster, D Vucic - Frontiers in cell and developmental biology, 2020 - frontiersin.org
… due to both inadequate NF-κB mediated innate responses and CD40 signal in B cells is a
… TNF stimulation in enteroids from these mice causes intestinal epithelial cell apoptosis, as …

[HTML][HTML] A new perspective of triptolide-associated hepatotoxicity: the relevance of NF-κB and NF-κB-mediated cellular FLICE-inhibitory protein

Z Yuan, Z Yuan, M Hasnat, H Zhang, P Liang… - … Pharmaceutica Sinica B, 2020 - Elsevier
… and overexpression of FLIP S rescued TP/TNF-α-induced apoptosis, implying the … in intestinal
epithelial cells or hepatocytes resulted in perinatal lethality as a consequence of apoptosis