Relationship between chronic hepatitis B virus infection and nature killer cells

J Zhang, Q Chen, H Feng - Viral Immunology, 2019 - liebertpub.com
NK cells and different clinical stages of chronic HBV infection … or hepatocellular carcinoma,
while the frequency of NK cellscell function, modulating the balance of activity and inhibitory …

[HTML][HTML] Role of immune cells in patients with hepatitis B virus-related hepatocellular carcinoma

HJ Cho, JY Cheong - International Journal of Molecular Sciences, 2021 - mdpi.com
… accepted that HBV infection induces the dysfunction of the … in NK cells obtained from
patients with HBV-related HCCHCC may be caused by the immune imbalance induced by …

… NKG2A and NKG2D expression is involved in NK cell immunosuppression and tumor progression of patients with hepatitis B virus‐related hepatocellular carcinoma

L Yu, L Sun, X Liu, X Wang, H Yan, Q Pu… - Hepatology …, 2023 - Wiley Online Library
… a virus-infected tumor environment, the imbalance between … of NK cells in the peripheral
blood of patients with HBV-HCC. … /NKG2D on NK cells is closely related to disease progression…

[HTML][HTML] Natural killer cells and T cells in hepatocellular carcinoma and viral hepatitis: current status and perspectives for future immunotherapeutic approaches

SG Kalathil, Y Thanavala - Cells, 2021 - mdpi.com
HBV infection and HCV infection the frequencies of NK cells … The functions of NK cells are
strictly regulated by the balance … + NK cells in the human liver indicates deteriorating disease

[HTML][HTML] HBV-induced immune imbalance in the development of HCC

Y Chen, Z Tian - Frontiers in immunology, 2019 - frontiersin.org
… with disease progression in HBV-related HCC patients (46). … cells was demonstrated to be
significantly less in HCC tumor … of NK cell functions during the progression of HBV infection. …

[PDF][PDF] Human CD96 correlates to natural killer cell exhaustion and predicts the prognosis of human hepatocellular carcinoma

H Sun, Q Huang, M Huang, H Wen, R Lin… - …, 2019 - Wiley Online Library
… the immune balance between three receptors in healthy hepatic NK cells is disrupted … NK
cell receptor imbalance and NK cell dysfunction in HBV infection and hepatocellular carcinoma

[HTML][HTML] Natural killer cell responses in hepatocellular carcinoma: implications for novel immunotherapeutic approaches

S Mantovani, B Oliviero, S Varchetta, D Mele… - Cancers, 2020 - mdpi.com
… -NK cells was able to delay disease progression of colorectal … as in chronic hepatitis B
and C virus infections, high levels of … and adaptive cells and where the balance between the …

[HTML][HTML] The role of natural killer cells in hepatocellular carcinoma development and treatment: A narrative review

S Juengpanich, L Shi, Y Iranmanesh, J Chen… - Translational …, 2019 - Elsevier
… of NK cells, their dysfunction due to several factors such as dysregulation of receptors and
their ligands, and imbalance … In summary, NK cells can directly kill cells infected with HBV and …

[HTML][HTML] Immune checkpoints on T and NK cells in the context of HBV infection: Landscape, pathophysiology and therapeutic exploitation

L Dumolard, C Aspord, PN Marche… - Frontiers in …, 2023 - frontiersin.org
… fibrosis, cirrhosis, and hepatocellular carcinoma (HCC) due to … in the regulation of the balance
between immune-mediated … of inhibitory receptors in inducing NK cell dysfunction. This is …

Natural killer cells involved in tumour immune escape of hepatocellular carcinomar

C Han, Y Jiang, Z Wang, H Wang - International immunopharmacology, 2019 - Elsevier
… an imbalance of activating and inhibitory receptors on NK cells, … dysfunction of NK cells are
involved in the progression of … of human hepatocellular carcinoma cells to NK cell cytotoxicity …