[HTML][HTML] Role of toll-like receptors and nod-like receptors in acute lung infection

J Le, Y Kulatheepan, S Jeyaseelan - Frontiers in Immunology, 2023 - frontiersin.org
… the activated caspase can then convert interleukin- (IL-1β) … (OMVs) released by
Acinetobacter baumannii, a Gram-… upregulates the NLRP3 inflammasome and leads to caspase-…

Sequential changes of NLRP3 inflammasome activation in sepsis and its relationship with death

…, A Díaz-Martín, A Gutiérrez-Pizarraya… - Shock, 2020 - journals.lww.com
… The inflammasome ultimately leads to the activation of … cytokines such as members of the
interleukin- (IL–1β) cytokine … in NLRP3-deficient rodents than in wild-type mice (15, 16) . …

[HTML][HTML] … and Anti-Inflammatory Potential of Liposomal Thymoquinone: Implications in the Treatment of Bacterial Pneumonia in Immunocompromised Mice

…, A Almatroudi, F Alrumaihi, A Aljaghwani… - Biomedicines, 2021 - mdpi.com
… In recent years, Acinetobacter baumannii infections have … an active immune system mediates
a protective immune response … the influx of inflammatory cells contributes to congestion and …

[HTML][HTML] Caspase-11 non-canonical inflammasomes in the lung

C Oh, A Verma, Y Aachoui - Frontiers in Immunology, 2020 - frontiersin.org
… The NLRP3 inflammasome is activated in response to the … mice register higher bacterial
burdens in the BALF and lungcontribute to the development of severe diseases in the lung. …

[HTML][HTML] Activation of the NLRP3 Inflammasome Pathway by Prokineticin 2 in Testicular Macrophages of Uropathogenic Escherichia coli- Induced Orchitis

Y Li, Y Su, T Zhou, Z Hu, J Wei, W Wang, C Liu… - Frontiers in …, 2019 - frontiersin.org
… are known to contribute to testicular inflammatory impairment, … The transcription of pro-inflammatory
genes, such as interleukin- … The bacterium Acinetobacter baumannii induced IL-1β …

[HTML][HTML] Innate immune responses in pneumonia

FT Korkmaz, KE Traber - Pneumonia, 2023 - Springer
… , directly contributes to immune defense in the lung against both … of interleukin-18 (IL-18) and
interleukin- (IL-1β). In addition, … Finally, mice deficient in NLRP3 or its associated adaptor …

[HTML][HTML] Pyroptosis and respiratory diseases: a review of current knowledge

J Sun, Y Li - Frontiers in Immunology, 2022 - frontiersin.org
… -driven airway inflammatory responses in mouse models of … (ACE2) leads to the activation
of the NLRP3 inflammasome. … that NLRP3 inflammasome mediators and IL-1β mediate the …

Neutrophil extracellular traps augmented alveolar macrophage pyroptosis via AIM2 inflammasome activation in LPS-induced ALI/ARDS

H Li, Y Li, C Song, Y Hu, M Dai, B Liu… - Journal of Inflammation …, 2021 - Taylor & Francis
… macrophage pyroptosis contribute to lung injury in mice. … We found that the levels of
interleukin- (IL-1β) and tumour … macrophages interact to mediate inflammation and lung injury …

Mechanisms and consequences of noncanonical inflammasome-mediated pyroptosis

SS Wright, SO Vasudevan, VA Rathinam - Journal of molecular biology, 2022 - Elsevier
NLRP3 inflammasome … or Acinetobacter baumannii infections.80, 81 Caspase-11 activation
has also been shown to trigger neutrophil extracellular traps and cell death and contribute to …

Chrysin prevents lipopolysaccharide-induced acute lung injury in mice by suppressing the IRE1α/TXNIP/NLRP3 pathway

M Chen, J Li, X Liu, Z Song, S Han, R Shi… - Pulmonary Pharmacology …, 2021 - Elsevier
… alveolar cell damage, which leads to pulmonary edema, … assay (ELISA) kits for testing
interleukin- (IL-1β), interleukin-6 (IL… , which results in the activation of the NLRP3