NLRX1 alleviates lipopolysaccharide-induced apoptosis and inflammation in chondrocytes by suppressing the activation of NF-κB signaling
D Ma, Y Zhao, J She, Y Zhu, Y Zhao, L Liu… - International …, 2019 - Elsevier
… OA, we hypothesized that NLRX1 may participate in OA through regulating NF-κB signaling.
… apoptosis, associated with preventing oxidative stress and sustaining mitochondrial activity […
… apoptosis, associated with preventing oxidative stress and sustaining mitochondrial activity […
NLRX1 knockdown attenuates pro-apoptotic signaling and cell death in pulmonary hyperoxic acute injury
HR Kim, MN Kim, EG Kim, JS Leem, SM Baek… - Scientific Reports, 2023 - nature.com
… in mitochondria 8,9 . Recent research has shown that NLRX1 has roles in modulation of
mitochondrial function, … NLRX1 deficiency dampens the inflammation and mortality induced by …
mitochondrial function, … NLRX1 deficiency dampens the inflammation and mortality induced by …
[HTML][HTML] NLRX1: versatile functions of a mitochondrial NLR protein that controls mitophagy
PY Bi, SA Killackey, L Schweizer, SE Girardin - Biomedical Journal, 2023 - Elsevier
… impact of NLRX1/UQCRC2 on mitochondrial function has not … and CNS, NLRX1 may dampen
inflammatory responses by … intrinsic apoptosis regulation occurs via NLRX1 interactions …
inflammatory responses by … intrinsic apoptosis regulation occurs via NLRX1 interactions …
Focusing on the cell type specific regulatory actions of NLRX1
… injury and apoptosis by decreasing oxidative stress in a mouse … to the sites of infection or
tissue injury. Within the peripheral … NLRX1 dampens oxidative stress and apoptosis in tissue …
tissue injury. Within the peripheral … NLRX1 dampens oxidative stress and apoptosis in tissue …
[HTML][HTML] NLRX1 is a multifaceted and enigmatic regulator of immune system function
… NLRX1 actually shuttles from the cytosol to the mitochondria … oxidative stress is also a key
driver of cell death through JNK … NLRX1 reportedly exerts protective effects against apoptosis …
driver of cell death through JNK … NLRX1 reportedly exerts protective effects against apoptosis …
The regulatory role of NLRX1 in innate immunity and human disease
M Liu, K Liu, D Cheng, B Zheng, S Li, Z Mo - Cytokine, 2022 - Elsevier
… homeostasis and metabolic balance, as well as apoptosis and … The interaction between
oxidative stress and autophagy has … of NLRX1 in the regulation of mitochondrial function, and …
oxidative stress and autophagy has … of NLRX1 in the regulation of mitochondrial function, and …
The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1
… The dependence of NLRX1 function on SARM1’s expression places NLRX1 as a protein …
to explain the function of NLRX1 and SARM1 in physiological and apoptotic conditions. Recent …
to explain the function of NLRX1 and SARM1 in physiological and apoptotic conditions. Recent …
NLRX1 Inhibits LPS-Induced Microglial Death via Inducing p62-Dependent HO-1 Expression, Inhibiting MLKL and Activating PARP-1
YL Huang, DY Huang, V Klochkov, CM Chan, YS Chen… - Antioxidants, 2024 - mdpi.com
… and PARP-1, we suggest an indirect action regulated by NLRX1 in the mitochondria to …
NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity…
NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity…
NLRX1: a key regulator in mitochondrial respiration and colorectal cancer progression
Y Ding, W Sun, M Han, Z Liu, H Kang, X Ma, J Wang… - Medical Oncology, 2024 - Springer
… in response to tissue injury and apoptosis [13]. It is now widely accepted that … NLRX1
dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity. J Exp …
dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity. J Exp …
NLRX1 deletion increases ischemia-reperfusion damage and activates glucose metabolism in mouse heart
H Zhang, Y Xiao, R Nederlof, D Bakker… - Frontiers in …, 2020 - frontiersin.org
… , anti-inflammatory mitochondrial NLRX1, affects IRI and … This study demonstrated that
NLRX1 reduces apoptosis and … how NLRX1 regulates mitochondrial function. A general …
NLRX1 reduces apoptosis and … how NLRX1 regulates mitochondrial function. A general …