The Role of NLRX1 in Mitochondrial Stress

S Killackey - 2021 - search.proquest.com
… from mitochondria that drive apoptosis include apoptosis-… in HG through increasing oxidative
stress and AMPK … viral infection, in which case NLRX1 dampens IFN signaling 279. MAVS …

[HTML][HTML] NLRX1 regulates TNF-α-induced mitochondria-lysosomal crosstalk to maintain the invasive and metastatic potential of breast cancer cells

K Singh, M Roy, P Prajapati, A Lipatova… - … et Biophysica Acta (BBA …, 2019 - Elsevier
NLRX1, a mitochondrial NOD family receptor protein, regulates mitochondrial function
during apoptosis and tissue injury. … and initiates ROS-dependent oxidative damage [10]. The …

Underlying mechanisms and related diseases behind the complex regulatory role of NOD-like receptor X1

H Shi, ZM Zhou, L Zhu, L Chen, ZL Jiang… - DNA and Cell …, 2022 - liebertpub.com
… It has been found that NLRX1 depletion impaired lysosomal function and… NLRX1 can protect
tubular epithelial cells from mitochondrial damage and apoptosis through an oxidative stress

NLRX1 deletion increases ischemia-reperfusion damage and activates glucose metabolism in mouse heart

H Zhang, Y Xiao, R Nederlof, D Bakker… - Frontiers in …, 2020 - frontiersin.org
… , anti-inflammatory mitochondrial NLRX1, affects IRI and … This study demonstrated that
NLRX1 reduces apoptosis and … how NLRX1 regulates mitochondrial function. A general …

NLRX1 Prevents M2 Macrophage Polarization and Excessive Renal Fibrosis in Chronic Obstructive Nephropathy

Y Liu, L Kors, LM Butter, G Stokman, N Claessen… - Cells, 2023 - mdpi.com
… hepatocytes and renal tubular cells, during cell stress and tissue injury [25,26]. To … NLRX1
dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity

NLRX1 enhances glutamate uptake and inhibits glutamate release by astrocytes

S Mahmoud, M Gharagozloo, C Simard, A Amrani… - Cells, 2019 - mdpi.com
… In the current work, using primary murine astrocyte cultures from WT and Nlrx1 -/- mice…
NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity

[PDF][PDF] Role of NLRX1 in glutamate uptake and release by astrocytes

S Mahmoud - 2019 - savoirs.usherbrooke.ca
… that by enhancing mitochondrial functions in astrocytes, NLRX1 … Moreover, NLRX1 inhibits
oxidative stress and apoptosis … production, and dampen oxidative stress. In the current work, …

NLRX1: a key regulator in mitochondrial respiration and colorectal cancer progression

Y Ding, W Sun, M Han, Z Liu, H Kang, X Ma, J Wang… - Medical Oncology, 2024 - Springer
… in response to tissue injury and apoptosis [13]. It is now widely accepted that … NLRX1
dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity. J Exp …

[引用][C] The involvement of NLRX1 in pulmonary hyperoxic acute injury

김혜린 - 2023

Activation of NLRX1 by NX-13 alleviates inflammatory bowel disease through immunometabolic mechanisms in CD4+ T cells

A Leber, R Hontecillas, V Zoccoli-Rodriguez… - The Journal of …, 2019 - journals.aai.org
NLRX1 is a mitochondria-associated receptor involved in … connections to the prevention of
oxidative stress (25, 38) and … NLRX1 has direct effects on NF-κB activity, the control of Gpx1, …