… is significantly lower with HFOT TRACHEAL than with HFOT NASAL , suggesting that the
physiologic effects of HFOT TRACHEAL are milder than HFOT NASAL . A gas flow of 50 L/min …

… High-flow nasal cannula (HFNC) oxygen therapy was first introduced into clinical practice
in … The gas is inhaled via a soft and comfortable silicone nasal cannula that fits without …

… novel devices for nasal delivery. This review described the structure and main characteristics
of the nasal cavity. The advantages, achievements and challenges of the nasal route use …

… that normalize nasal physiology (as measured by CFD-derived measures of nasal patency)?
[… scores), can the same improvement in nasal physiology be achieved with less surgery? [4] …

… nasal cavity) may influence drug pharmacokinetics. Most approved nasal migraine therapies
target the lower nasal … , the upper nasal space harnesses the benefits of nasal delivery to …

… nasal pathways remained unexplored until in 1991. William Frey II proposed a patent for a
nasal drug … Subsequently, there was an increased interest in nasal delivery especially for the …

… provide physiologic information such as nasal airflow distribution and nasal resistance. These
results demonstrate the strong potential of CFD modeling in quantifying nasal patency and …

… nasal cavity wall, we present computational model development, and evaluation of mucus
motion on a realistic nasal … approaches based on the actual nasal cavity geometry namely: (i) …

… This work delivers a set of methods suitable for the assessment of excipients for nasal
powders and nasal powder formulations. Adhesiveness on agar–mucin plates, rheological tests, …

… Quality of life is not affected and although small septal perforations and synechiae can be
observed, nasal physiology is not compromised. Nonetheless, careful manipulation of …