… 2H-thiochroman derivatives, including thiochromenes, … ), was reported to have anti-trypanosomal
activity by Dipak Harel … similarities to the anti-trypanosomal compound quercetin, was …

… largest classes of derivatives, the majority of which had IC 50 values low enough to indicate
that natural product derivatives can be an important source of potential new drugs to treat …

… recent literature reports on chromene as a … -chromenes, natural benzochromenes and fused
chromenes, but also highlights the need for further research on reported and new chromene-…

… Based on the high importance of the chromene scaffold, we … to obtain new chromenes
and derivatives possessing … the natural source of chromene and its derivatives along with …

… and aromatic amides, alkaloids, polyketides, benzoic acid derivatives, and chromenes,
among which trypanocidal activity was reported for lignans and benzoic acid derivatives [17, 18]. …

… to check the importance of the nitro substituent at the aromatic ring in LY290181(herein
designed by the number 18) to its antiproliferative properties, we decided to treat chromenes 15 …

… Several amides and chromene compounds with potent trypanocidal activity were … agents.
For these compounds, the presence of ester group is 10-fold more potent than chromenes …

… of natural and synthesized 4H-chromenes and 4H-benzochromenes are used as
effective reagents against asthma, anti-trypanosomal, … However, the substituted 4H-benzo[h]chromenes …

… The chromene scaffolds which act as … of chromene derivatives has been reported to act as
efficient apoptosis inducers 5, DNA polymerase β-inhibitors 6 and anti-trypanosomal agents 7,…

… All the reagents used in this work for the synthesis of chromene derivatives are purchased
from Avra and were used without further purification. Custom-made microwave oven having …