Phytochemicals as modulators of β-cells and immunity for the therapy of type 1 diabetes: Recent discoveries in pharmacological mechanisms and clinical potential

MK Apaya, TF Kuo, MT Yang, G Yang, CL Hsiao… - Pharmacological …, 2020 - Elsevier
Natural products, primarily phytochemicals, are an … In this review, we focus on recent progress
in the understanding of the … promising phytochemicals with immune modulatory activities

[HTML][HTML] Anti-inflammatory phytochemicals for the treatment of diabetes and its complications: Lessons learned and future promise

M Kong, K Xie, M Lv, J Li, J Yao, K Yan, X Wu… - Biomedicine & …, 2021 - Elsevier
… a huge burden on global medical resources, despite the availability … In this review, we aim
to discuss recent advances in the … : type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (…

Medicinal plants and phytochemicals regulating insulin resistance and glucose homeostasis in type 2 diabetic patients: a clinical review

A Mahdavi, M Bagherniya, MS Mirenayat… - … of Plant-Derived Natural …, 2021 - Springer
… In a double-blind clinical trial study, 21 patients with T2DM … individuals with diabetes without
any treatment were considered … and phytochemicals that may elicit antioxidant activities and …

[HTML][HTML] Pharmaceutical drugs and natural therapeutic products for the treatment of type 2 diabetes mellitus

J Blahova, M Martiniakova, M Babikova, V Kovacova… - Pharmaceuticals, 2021 - mdpi.com
… In this review, both pharmaceutical drugs and selected naturalclinical conditions associated
with T2DM include diabetic … They are often considered natural phytochemicals. Polyphenols …

[HTML][HTML] SIRT1 activation by natural phytochemicals: an overview

C Iside, M Scafuro, A Nebbioso, L Altucci - Frontiers in pharmacology, 2020 - frontiersin.org
review will examine compounds of natural origin recently found to upregulate SIRT1 activity,
… Many clinical studies conducted in healthy patients and volunteers using both high and low …

Effects of phytochemicals against diabetes

M Bacanli, SA Dilsiz, N Başaran, AA Başaran - Advances in food and …, 2019 - Elsevier
Phytochemicals derived from natural plants have been used … Type 1 diabetes mellitus: This
form of diabetes is also called … are many clinical trials showing catechin against diabetes and …

[HTML][HTML] Pharmacologically active phytomolecules isolated from traditional antidiabetic plants and their therapeutic role for the management of diabetes mellitus

P Ansari, S Akther, JMA Hannan, V Seidel, NJ Nujat… - Molecules, 2022 - mdpi.com
… an older population than Type 1 diabetes [5]. Both forms of … phytochemicals and have been
traditionally used for treating … in clinical use to establish the benefits and mode(s) of action of …

[HTML][HTML] Phytochemicals as potential epidrugs in type 2 diabetes mellitus

K Ramirez-Alarcon, M Victoriano, L Mardones… - Frontiers in …, 2021 - frontiersin.org
… In this sense, in this review the epigenetic mechanisms … studies and clinical trials, addressing
the phytochemicals with … Binding of type 1 insulin-like growth factor (IGF-1) to its tetrameric …

Novel phytochemical constituents and their potential to manage diabetes

SI Khalivulla, A Mohammed… - Current Pharmaceutical …, 2021 - ingentaconnect.com
… with antidiabetic activities were elucidated in the present review. In … Further, molecular and
clinical trials are required to select … of insulin hormone; type-1 diabetes that results due to the …

Medicinal plants and phytochemicals for diabetes mellitus: Pharmacokinetic characteristics and herb-drug interactions

DG Han, SS Cho, JH Kwak, IS Yoon - Journal of Pharmaceutical …, 2019 - Springer
… The aim of this article is to provide an updated review of the … Low levels (or absence) of
insulin leads to type 1 diabetes, … In a randomized clinical study, 60 diabetic patients were divided …