The impact of intrauterine growth restriction and prematurity on nephron endowment
MR Sutherland, MJ Black - Nature Reviews Nephrology, 2023 - nature.com
… renal filtration surface area, and therefore diminished renal … susceptibility to the later
development of kidney disease. … capillary growth compared with that of unventilated control sheep …
development of kidney disease. … capillary growth compared with that of unventilated control sheep …
Renal morphology and glomerular capillarisation in young adult sheep born moderately preterm
MR Sutherland, W Malik, VB Nguyen, V Tran… - … Origins of Health and …, 2021 - cambridge.org
… length, surface area and total renal filtration surface area in the … length and surface area,
and the morphology of the kidneys, in … on nephron endowment in the preterm baboon kidney. …
and the morphology of the kidneys, in … on nephron endowment in the preterm baboon kidney. …
Structural and functional changes in the kidney caused by adverse fetal and neonatal environments
M Awazu - Molecular Biology Reports, 2022 - Springer
… growth restriction (IUGR), the following … development was reported to be altered in preterm
sheep. Thus glomerular capillary length, surface area, and total kidney filtration surface area …
sheep. Thus glomerular capillary length, surface area, and total kidney filtration surface area …
Physiology and pathophysiology of compensatory adaptations of a solitary functioning kidney
Z McArdle, MF Schreuder, KM Moritz… - Frontiers in …, 2020 - frontiersin.org
… and an increase in single nephron glomerular filtration rate (… suggest that the total nephron
endowment in congenital SFK … In sheep with congenital SFK, the renal responses to systemic …
endowment in congenital SFK … In sheep with congenital SFK, the renal responses to systemic …
[HTML][HTML] Low nephron endowment increases susceptibility to renal stress and chronic kidney disease
… the single-nephron glomerular filtration rate (GFR). These … While glomerular surface area
increased between 2 and 6 … long-term renal adverse effects following neonatal AKI in the …
increased between 2 and 6 … long-term renal adverse effects following neonatal AKI in the …
Programming of renal development and chronic disease in adult life
ER Lumbers, Y Kandasamy, SJ Delforce… - Frontiers in …, 2020 - frontiersin.org
… between 90 and 120 mL/min/1.73 m 2 body surface area. … Thus, oligonephropathy caused
by fetal growth restriction or in … in the development of hypertension in young sheep whose …
by fetal growth restriction or in … in the development of hypertension in young sheep whose …
Clinical consequences of developmental programming of low nephron number
VA Luyckx, BM Brenner - The Anatomical Record, 2020 - Wiley Online Library
… growth restriction are associated with reduced nephron … sheep, congenital or surgical loss
of nephrons during fetal … In contrast, kidney volume related to body surface area (BSA) at age …
of nephrons during fetal … In contrast, kidney volume related to body surface area (BSA) at age …
[HTML][HTML] Brenner & Rector's the Kidney
V Luyckx, K Skorecki, PA Marsden, GM Chertow - 2019 - doctorlib.info
… in nephron number and whole kidney glomerular surface area … rats or fetal uninephrectomy
in sheep, that is, loss of nephrons at a … in utero in fetuses subjected to growth restriction. [84] …
in sheep, that is, loss of nephrons at a … in utero in fetuses subjected to growth restriction. [84] …
[PDF][PDF] Strategies to prevent glomerular hyperfiltration injury in congenital solitary kidneys
Z McArdle - 2021 - repository.ubn.ru.nl
… by removal of a kidney from the sheep fetus at gestation day 100… pressure and increase in
the filtering surface area.These … These findings also suggest that the total nephron endowment …
the filtering surface area.These … These findings also suggest that the total nephron endowment …
Nephron number and its determinants: a 2020 update
JR Charlton, EJ Baldelomar, DM Hyatt, KM Bennett - Pediatric Nephrology, 2021 - Springer
… , excluding those with intrauterine growth restriction and … a lower nephron endowment
may be at higher risk for kidney … fundamental understanding of kidney filtration, removed from …
may be at higher risk for kidney … fundamental understanding of kidney filtration, removed from …