Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised …
Background In laboratory animals, exposure to most general anaesthetics leads to
neurotoxicity manifested by neuronal cell death and abnormal behaviour and cognition.
Some large human cohort studies have shown an association between general anaesthesia
at a young age and subsequent neurodevelopmental deficits, but these studies are prone to
bias. Others have found no evidence for an association. We aimed to establish whether
general anaesthesia in early infancy affects neurodevelopmental outcomes. Methods In this …
neurotoxicity manifested by neuronal cell death and abnormal behaviour and cognition.
Some large human cohort studies have shown an association between general anaesthesia
at a young age and subsequent neurodevelopmental deficits, but these studies are prone to
bias. Others have found no evidence for an association. We aimed to establish whether
general anaesthesia in early infancy affects neurodevelopmental outcomes. Methods In this …
[PDF][PDF] Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS)
(Word count: 365) 91 Background: In laboratory animals, exposure to most general
anaesthetics leads to neurotoxicity 92 manifested by neuronal cell death, and abnormal
behaviour and cognition. Some, everal large 93 human cohort studies demonstrate an
association between general anaesthesia at a young age and 94 subsequent
neurodevelopmental deficits, but are prone to bias. Others have found no evidence 95 for an
association. We aimed to establish whether general anaesthesia in early infancy has an 96 …
anaesthetics leads to neurotoxicity 92 manifested by neuronal cell death, and abnormal
behaviour and cognition. Some, everal large 93 human cohort studies demonstrate an
association between general anaesthesia at a young age and 94 subsequent
neurodevelopmental deficits, but are prone to bias. Others have found no evidence 95 for an
association. We aimed to establish whether general anaesthesia in early infancy has an 96 …
以上显示的是最相近的搜索结果。 查看全部搜索结果