… New neuroprotective therapies for severe traumatic brain injury (TBI) have not translated …
How might we address this deficiency in translational design? Looking back at OBTT, and to …

… Ischemic stroke and traumatic brain injury (TBI) are among the leading causes of death and
… therapeutic options to increase neural repair and recovery as they promote neuroprotection …

… of injury induced, and their clinical relevance. Third, we defined the concept of neuroprotection
and … Then, we reviewed post-TBI neuroprotective treatments with a focus on the following …

… brain damage, along with targeted current and potential neuroprotective therapeutic …
antagonists after acute brain injury, illustrate the translational challenges involved in limiting …

… events, which aggravate brain damage, can be prevented by an effective strategy …
neuroprotection. Two major forms of CNS injury are traumatic brain injury (TBI) and spinal cord injury …

… , a neuroprotective therapeutic has yet to be approved for the treatment of acute brain injuries
such as stroke or traumatic brain injury. … translational research and clinical trial challenges …

… result of brain trauma, we can therefore divide TBI into primary and secondary brain injuries
[… A neuroprotective therapy, therefore, should primarily address inhibition of the severe and …

… neuroprotective agents. The aim of this work is to review TBI pathophysiology and existing
and potential new therapeutic … Because of the failure of translational therapies focused on …

… The paucity of female subjects in brain injury research may impede the development of TBI
… TBI therapy as estrogen and progesterone have been examined for potential neuroprotective …

… ways to improve translational success in neuroprotection research and emerging therapies.
To do this, analysis of why translational research in neuroprotection fails necessitates …