… DFP is an iron chelator widely used for the treatment of thalassemia and other systemic iron
overload diseases, showing high affinity and selectivity for iron.29, 30 The characteristics of …

… Novel iron chelating agents such as natural remedies are useful to decrease the side effects
of iron in the … A study investigated the neuroprotective and chelating capacities of green tea …

… and some other neuroprotective and neurorestorative effects [104]. Multifunctional iron
chelators … are required to develop iron-trapping agents that are highly selective, low affinity, BBB …

… In iron-deficient cells, IRPs selectively bind IRE at 5 UTR of the mRNA coding for ferritin
and … by which it exerts neuroprotective activity is through decreasing redox-active iron [170]. …

… of the irreversible selective MAO-B inhibitor and neuroprotective/neurorestorative drug,
rasagiline, … iron chelator-brain selective monoamine oxidase-A/monoamine oxidase-B inhibitor in …

… as a result of chelation by desferrioxamine and clioquinol, translation of APP was selectively
down-regulated. APP interacts with Fpn, and it has ferroxidase activity as it possessed the …

… Ferroptosis is a novel type of cell death characterized by iron-… Building on these findings,
we can selectively induce … Another study showed that Fer-1 had a significant neuroprotective …

… B) with different substrate selectivity and tissue expression patterns led to novel therapeutic
… is a multitarget iron chelator that exhibits brain-selective MAO inhibition and neuroprotection …

… a longer duration and exhibit neuroprotective effects against various … novel multifunctional
agents with D 3 -preferring agonist activity along with antioxidant activity, such as the selective …

… It is characterized by selective loss of dopaminergic neurons … The neuroprotective activities
can prevent or slow down the … optimization of novel ligands with enhanced activity against …