Calycosin Alleviates Paraquat-Induced Neurodegeneration by Improving Mitochondrial Functions and Regulating Autophagy in a Drosophila Model of Parkinson's …

HS Chaouhan, X Li, KT Sun, IK Wang, TM Yu, SH Yu… - Antioxidants, 2022 - mdpi.com
… We used an environmental neurotoxin-induced Drosophila … with neuroprotective efficacy
against PQ-induced neurotoxicity. … neuroprotective role against PQ-mediated DA neuron loss. …

[PDF][PDF] Protective potential of Lannea microcarpa fruit pulp extract on paraquat-induced oxidative stress and locomotor deficits in Drosophila melanogaster.

HOB Oloyede, AO Adeleye, FA Ariyo… - …, 2020 - ojs.klobexjournals.com
Decalepis hamiltonii root extract attenuates the age-related decline in the … Neuroprotective
effect of geraniol and curcumin in an acrylamide model of neurotoxicity in Drosophila

Potentiation of paraquat toxicity by inhibition of the antioxidant defenses and protective effect of the natural antioxidant, 4-hydroxyisopthalic acid in Drosophila …

S Niveditha, T Shivanandappa - … and Physiology Part C: Toxicology & …, 2022 - Elsevier
… Our study reinforces the critical role of oxidative stress in the neurotoxicity of PQ and the
therapeutic potential of the natural antioxidant, DHA-I, against neurodegenerative diseases. …

Protective effect of Bougainvillea glabra Choisy bract in toxicity induced by Paraquat in Drosophila melanogaster

AC Caurio, JR Boldori, LM Gonçalves… - … and Physiology Part C …, 2024 - Elsevier
… against Paraquat-induced toxicity in Drosophila melanogaster. … Paraquat-induced oxidative
stress and neurotoxicity were … the protective potential of Decalepis hamiltonii (Dh) root …

Neuroprotective action of aspirin on Paraquat intoxication in on Drosophila melanogaster

MKB do Carmo, MOV Figueiredo… - Research, Society and …, 2021 - rsdjournal.org
… We investigated aspirin's potential neuroprotective effects against paraquat-induced neurotoxicity
(PQ) in … PQ-induced neurotoxicity has also been associated with a marked decrease in …

Exploring the Efficient Natural Products for the Therapy of Parkinson's Disease via Drosophila Melanogaster (Fruit Fly) Models

W Zhang, Y Ju, Y Ren, Y Miao, Y Wang - Current Drug Targets, 2024 - ingentaconnect.com
… These natural products exert neuroprotective effects through various … protective effect of
Decalepis hamiltonii in paraquat-inducedparaquat-induced oxidative stress and neurotoxicity in …

The Drosophila Model: Exploring Novel Therapeutic Compounds against Neurodegenerative Diseases

SJ Cha, HA Do, HJ Choi, M Lee, K Kim - Antioxidants, 2019 - mdpi.com
… that may lead to neuroprotection [59,60]. The neuroprotective impacts of coffee and tobacco
were … For example, the root extract of Decalepis hamiltonii (Dh) is known as a novel natural …

Ameliorative Role of Nutraceuticals on Neurodegenerative Diseases Using the Drosophila melanogaster as a Discovery Model to Define Bioefficacy

R Himalian, SK Singh, MP Singh - Journal of the American …, 2022 - Taylor & Francis
… for neuroprotective effects exploiting the fruit fly Huntington poly-Q … The neuroprotective
impact of Bacopa has conjointly been … , morbidness, and neurotoxicity in fruit flies (Citation110). …

LRRK2 Kinase Inhibitor PF-06447475 Protects Drosophila melanogaster against Paraquat-Induced Locomotor Impairment, Life Span Reduction, and Oxidative Stress

DA Quintero-Espinosa, M Jimenez-Del-Rio… - Neurochemical …, 2024 - Springer
… Indeed, LRRK2 kinase has been found to be responsible for OS-induced neurotoxicity [10].
In … In fact, the PQ-Drosophila model has been used to interrogate potential neuroprotective

Enhanced accumulation of reduced glutathione by Scopoletin improves survivability of dopaminergic neurons in Parkinson's model

P Pradhan, O Majhi, A Biswas, VK Joshi… - Cell Death & Disease, 2020 - nature.com
… in paraquat-induced oxidative stress model was tested by exposing Oregon R + Drosophila
Neuroprotective effects of methanolic extract of avocado Persea americana (var. Colinred) …