The role of brain derived neurotrophic factor in central nervous system

Y Li, F Li, D Qin, H Chen, J Wang, J Wang… - Frontiers in Aging …, 2022 - frontiersin.org
Brain derived neurotrophic factor (BDNF) has multiple biological functions which are … B (TrkB)
receptor and the p75 neurotrophin receptor, involving in physiological and pathological …

Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive Tract

R Chow, JM Wessels, WG Foster - Human Reproduction Update, 2020 - academic.oup.com
… Of the neurotrophins, the literature describing the expression and function of brain-derived
neurotrophic factor (BDNF) and its high-affinity receptor, neurotrophin receptor kinase-2 (…

Effects of neurotrophic factors in glial cells in the central nervous system: expression and properties in neurodegeneration and injury

S Pöyhönen, S Er, A Domanskyi… - Frontiers in physiology, 2019 - frontiersin.org
neurons in vitro. This led to the discovery of the potent dopamine neurotrophic factor, glial
cell line-derived neurotrophic … between glia and NTFs including neurotrophins, GDNF-family …

Mechanisms that modulate and diversify BDNF functions: implications for hippocampal synaptic plasticity

AP De Vincenti, AS Ríos, G Paratcha… - Frontiers in cellular …, 2019 - frontiersin.org
… is mediated in a cell-intrinsic manner by neurotrophin signaling. In this system, the
knockdown of Lrig1, which promotes TrkB activation, accelerates neuronal development and …

Nerve growth factor pathobiology during the progression of Alzheimer's disease

EJ Mufson, SE Counts, SD Ginsberg… - Frontiers in …, 2019 - frontiersin.org
… factor (NGF) underlies the selective survival of cultured neurons. They were the first to suggest
the neurotrophic hypothesis of neuronal survival. NGF is a product of a single gene found …

The role of NADPH oxidases in neuronal development

A Terzi, DM Suter - Free Radical Biology and Medicine, 2020 - Elsevier
development and adulthood. Here, we review the role of Nox-mediated ROS during CNS
development… to signaling in neural stem cell maintenance and neuronal differentiation, as well …

Neurotrophins and glial cell line-derived neurotrophic factor in the ovary: physiological and pathophysiological implications

HM Chang, HC Wu, ZG Sun, F Lian… - Human reproduction …, 2019 - academic.oup.com
… paracrine regulation of ovarian function in humans remains … functional roles of NTs and
GDNF in human ovarian biology and disorders, and to describe and propose the development of …

Brain-derived neurotrophic factor (BDNF): novel insights into regulation and genetic variation

M Notaras, M van den Buuse - The Neuroscientist, 2019 - journals.sagepub.com
… An interesting question surrounding mBDNF-TrkB signaling is, how contained are the
neurotrophic functions of BDNF to TrkB? Does mBDNF-TrkB signaling depend at all on the co-…

Role of Zeb2/Sip1 in neuronal development

E Epifanova, A Babaev, AG Newman, V Tarabykin - Brain Research, 2019 - Elsevier
… plays essential role in neuronal development. Sip1 … neuronal development. This review
addresses the molecular pathways acting downstream of Zeb2 that cause brain development

Recent advances on the role of brain-derived neurotrophic factor (BDNF) in neurodegenerative diseases

KF Azman, R Zakaria - International journal of molecular sciences, 2022 - mdpi.com
brain development. ProBDNF is higher in the early postnatal period, when it is important
for the development of brain function, while mBDNF is higher in adulthood for brain function, …