… In summary, ~82% (348 loci) of the 424 identified eGFRcrea loci were validated by … relevant
for kidney function. Our results underscore the value of eGFRcys to kidney function GWAS, …

… signals impact on kidney function, we expand the COGENT-Kidney Consortium in this …
With these data, we identify novel loci and distinct associations for kidney function, assess …

… replicated in 42,166 individuals, identified 24 new loci associated with eGFR (BCAS1, AP5B1,
A1CF, … of the mechanisms of kidney function and disease, and improve disease prediction. …

… associated with kidney function and CKD prevalence in a large Japanese population 55
where IL-4 was found to be associated … of end-stage renal disease patients showing that those …

… Genetic variants related to the presence and degree of microalbuminuria and … in kidney
function [21]. DNA variants in APOL1 have been shown to be associated with non-diabetic CKD …

… kidney injury (95% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney
function … mechanisms and individuals at risk for sustained deterioration of kidney function. …

… the Chronic Renal Insufficiency Cohort for DKD phenotypes, including glycemic control,
albuminuria, kidney function, and kidney function decline. We show distinct methylation patterns …

… key roles of proximal tubules and metabolism in kidney function regulation. Furthermore, the
causal role of SLC47A1 in kidney disease … To identify new loci, we first collected the leading …

… DKD is now the main cause of chronic kidney disease (CKD) worldwide and the leading
cause of end-stage-renal disease (ESRD) requiring renal replacement therapy (dialysis or …

… studies and new algorithms, we explored the potential of using a PRS for kidney function as
… strength of associations of the PRS with incident kidney diseases over 30 years of follow-up …