The use of a next-generation sequencing-derived machine-learning risk-prediction model (OncoCast-MPM) for malignant pleural mesothelioma: a retrospective study

MG Zauderer, A Martin, J Egger, H Rizvi… - The Lancet Digital …, 2021 - thelancet.com
Cancer Targets (MSK-IMPACT). We collected clinical, pathological, and routine next-generation
sequencing … treated at the Memorial Sloan Kettering Cancer Center (New York, NY, USA)…

Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1)

…, Japanese Society of Medical Oncology… - … of Clinical Oncology, 2021 - Springer
… are expected to be used to predict the efficacy of drug therapies and to classify, definitively
… role in the conventional genetic testing. It is mandated that cancer genomic profiling tests be …

[HTML][HTML] Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese …

X Zhang, Z Liang, S Wang, S Lu, Y Song… - Cancer biology & …, 2019 - ncbi.nlm.nih.gov
… of tumor gene testing, NGS for precision diagnostics has gradually progressed from single-gene
analysis to the profiling of several hundreds of genes… , molecular classification of tumors

Next-generation sequencing-based clinical sequencing: toward precision medicine in solid tumors

T Wakai, P Prasoon, Y Hirose, Y Shimada… - … of clinical oncology, 2019 - Springer
… for the classification of tumor type sub-categories based on genetic alterations in solid …
technology for genetic screening. Together with the advancement of NGS, cancer DNA testing has …

Next-generation sequencing improves diagnosis, prognosis and clinical management of myeloid neoplasms

D Carbonell, J Suárez-González, M Chicano… - Cancers, 2019 - mdpi.com
Molecular diagnosis of myeloid neoplasms (MN) is based on the detection of multiple genetic
… It allows to improve diagnosis, refine classification of prognosis and provide patients with …

Next-generation sequencing data for use in risk assessment

BA Merrick - Current opinion in toxicology, 2019 - Elsevier
… , short read archive, molecular diagnostic assays, and others. … DNA used for tumor diagnosis
in oncology might be similarly … Use of ccfDNA has gained attention in the diagnosis, staging

[HTML][HTML] Application of next generation sequencing in laboratory medicine

Y Zhong, F Xu, J Wu, J Schubert… - Annals of laboratory …, 2021 - synapse.koreamed.org
… NGS in inherited diseases, oncology, and infectious diseases… research to clinical diagnosis,
molecular diagnosis rate, and … , as variant classification and new gene discovery advances. …

A comprehensive DNA panel next generation sequencing approach supporting diagnostics and therapy prediction in neurooncology

J Lorenz, T Rothhammer-Hampl, S Zoubaa… - Acta Neuropathologica …, 2020 - Springer
… comprehensively support molecular testing in neurooncology… CNS tumors classified according
the WHO 2016 classification … , neurosurgeon, medical oncologist) 3 patients were chosen …

Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group

F Mosele, J Remon, J Mateo, CB Westphalen… - … of Oncology, 2020 - Elsevier
… centres perform multigene sequencing in the context of molecular screening programmes in
order to … the main molecular variations classified by ESCAT in advanced squamous NSCLC. …

Machine learning for genetics-based classification and treatment response prediction in cancer of unknown primary

I Moon, J LoPiccolo, SC Baca, LM Sholl, KL Kehl… - Nature Medicine, 2023 - nature.com
… trained on targeted next-generation sequencing (NGS) data from 36,445 tumors across
22 … record for 158 patients with CUP by a certified oncologist, we identified 20 patients (12.7%) …