Nicotine downregulates microRNA‐200c to promote metastasis and the epithelialmesenchymal transition in human colorectal cancer cells

Z Lei, Y Xiaomin, H He, C Jian… - Journal of cellular …, 2019 - Wiley Online Library
… SW620 and HT-29 CRC cell lines. Nicotine induced cell proliferation, migration, and invasion
and promoted the epithelialmesenchymal transition in SW620 and HT-29 cells, and these …

Nicotine promotes tumor progression and epithelial-mesenchymal transition by regulating the miR-155-5p/NDFIP1 axis in pancreatic ductal adenocarcinoma

Q Ben, Y Sun, J Liu, W Wang, D Zou, Y Yuan - Pancreatology, 2020 - Elsevier
nicotine-induced cellular functions of PDAC cells in vitro, we knocked down the expression
of miR-155-5p in Panc-1 and SW1990 cellsnicotine-induced cellular functions of PDAC cells

[HTML][HTML] Elevation of O-GlcNAc and GFAT expression by nicotine exposure promotes epithelialmesenchymal transition and invasion in breast cancer cells

N Zhang, T Zhu, K Yu, M Shi, X Wang, L Wang… - Cell death & …, 2019 - nature.com
Nicotine (Nic), an active component of tobacco, has been found to induce epithelial-mesenchymal
transition (EMT) in breast cancer cells. However, the alterations in protein O-…

Nicotine promotes cervical metastasis of oral cancer by regulating peroxiredoxin 1 and epithelialmesenchymal transition in mice

M Wang, W Niu, M Qi, H Chen, M Zhang… - OncoTargets and …, 2019 - Taylor & Francis
… that nicotine induced cell proliferation and Prx1 overexpression in OSCC … nicotine induced
invasion and cervical metastasis via regulating Prx1 and EMT in oral cancer CAL 27 cells. …

α7-Nicotinic Acetylcholine Receptor Promotes Cholangiocarcinoma Progression and EpithelialMesenchymal Transition Process

S Chen, X Kang, G Liu, B Zhang, X Hu… - Digestive Diseases and …, 2019 - Springer
cell lines generated by shRNA lentivirus transfection to investigate the biological functions of
α7-nAChR in proliferation… to detect apoptosis and epithelialmesenchymal transition (EMT)-…

Transcription factor SP1 and oncoprotein PPP1R13L regulate nicotine-induced epithelial-mesenchymal transition in lung adenocarcinoma via a feedback loop

H Zhang, G Zhang, J Zhang, M Xiao, S Cui, S Wu… - Biochemical …, 2022 - Elsevier
… program required for the invasion and metastasis in tumor cells. … nicotine-induced EMT
process, the present study established an EMT cell model of lung cancer using 1 μM of nicotine, a …

The potential role of nicotine in breast cancer initiation, development, angiogenesis, invasion, metastasis, and resistance to therapy

Z Khodabandeh, M Valilo, K Velaei… - Breast Cancer, 2022 - Springer
… p38 MAPK, while nicotine-induced cell proliferation relies on Erk1/… Nicotine promotes the
mobility and aggression of breast cancer cells [76] as well as epithelial mesenchymal transition (…

Nicotine-induced oxidative stress contributes to EMT and stemness during neoplastic transformation through epigenetic modifications in human kidney epithelial cells

YW Chang, KP Singh - Toxicology and applied pharmacology, 2019 - Elsevier
… To evaluate the role of ROS in nicotine-induced cell growth, MTT assay was performed. The
nicotine exposure increased cell growth in both 1 μM and 10 μM nicotine exposed cells by …

The Natural Compound Dehydrocrenatidine Attenuates NicotineInduced Stemness and EpithelialMesenchymal Transition in Hepatocellular Carcinoma by …

CL Li, CC Wang, HT Pai, SL Tu, PY Hou… - Disease …, 2022 - Wiley Online Library
… the effect of nicotine on HCC cell proliferation, both the Huh7 and HepG2 cells were titrated
… DHCT reversed nicotine induces cell migratory, invasive, and EMT properties in Huh7 and …

[HTML][HTML] A nicotine-induced positive feedback loop between HIF1A and YAP1 contributes to epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma

Q Ben, W An, Y Sun, A Qian, J Liu, D Zou… - Journal of Experimental & …, 2020 - Springer
… Exposure to smoking or nicotine promoted EMT and tumor growth in PDAC cells and in
xenograft … These results indicate that nicotine induces HIF1A and YAP1 expression through the …