[HTML][HTML] Electrophilic characteristics and aqueous behavior of fatty acid nitroalkenes
V Grippo, M Mojovic, A Pavicevic, M Kabelac… - Redox biology, 2021 - Elsevier
… -formed NO 2 -FA or a combination of precursor fatty acids and sources of the organic nitrates
required for fatty acid nitration … in characterizing the biophysical and biochemical properties …
required for fatty acid nitration … in characterizing the biophysical and biochemical properties …
The nitration of proteins, lipids and DNA by peroxynitrite derivatives-chemistry involved and biological relevance
JM Pérez de la Lastra, CA Juan, FJ Plou… - Stresses, 2022 - mdpi.com
… , the exact process by which fatty acids are nitrated in vivo is unclear as yet [47]. However,
nitrated unsaturated fatty acids have chemically electrophilic characteristics that allow them to …
nitrated unsaturated fatty acids have chemically electrophilic characteristics that allow them to …
[HTML][HTML] Tomato pomace-derived nitrated fatty acids: Synthesis and antiplatelet activity
L Rodríguez, F Lagos, M Mastrogiovanni… - Biomedicine & …, 2024 - Elsevier
… fatty acids found in tomato pomace undergo nitration during digestion. Our hypothesis aims
to explore the formation of nitrated fatty acids (… Chemical characterization of tomato pomace …
to explore the formation of nitrated fatty acids (… Chemical characterization of tomato pomace …
Nitro-fatty acid logistics: formation, biodistribution, signaling, and pharmacology
FJ Schopfer, NKH Khoo - Trends in Endocrinology & Metabolism, 2019 - cell.com
… of monounsaturated and bis-allylic FAs: this nitration mechanism is inefficient as the initial
addition of • NO 2 results in an unstable radical. The radical intermediate reverses back to the …
addition of • NO 2 results in an unstable radical. The radical intermediate reverses back to the …
The nitrated fatty acid, 10-nitrooleate inhibits the neutrophil chemotaxis via peroxisome proliferator-activated receptor gamma in CLP-induced sepsis in mice
… Nitrated fatty acids (NFA) such as 10-nitrooleate (OA-NO 2 ), nitrolinoleic acid etc. produced
… unsaturated fatty acids [12,13], have been identified as one of the largest single pools of …
… unsaturated fatty acids [12,13], have been identified as one of the largest single pools of …
Nitro-fatty acids as activators of hSIRT6 deacetylase activity
… acid promoted H3K9 deacetylation, whereas oleic acid had no effect. Altogether, our results
show that nitrated fatty acids … should be considered as a molecular target for in vivo actions …
show that nitrated fatty acids … should be considered as a molecular target for in vivo actions …
A physiological perspective on targets of nitration in NO-based signaling networks in plants
M Arasimowicz-Jelonek… - Journal of …, 2019 - academic.oup.com
… The nitration process can be specifically involved in various cell regulatory mechanisms
that control redox signaling via nitrated cGMP or nitrated fatty acids. In addition, there is …
that control redox signaling via nitrated cGMP or nitrated fatty acids. In addition, there is …
Post-translational modification of proteins mediated by nitro-fatty acids in plants: nitroalkylation
… Recent knowledge has illustrated the formation of RLS that … Specifically, we will argue
the biological properties of … of the nitration of unsaturated fatty acids in humans. Dietary …
the biological properties of … of the nitration of unsaturated fatty acids in humans. Dietary …
Electrophilic fatty acid nitroalkenes are systemically transported and distributed upon esterification to complex lipids [S]
… Supported by HPLC-high-resolution-MS/MS analysis of synthetic and plasma-… key mechanism
of NO 2 -FA distribution is an initial esterification into complex lipids. Quantitative analysis …
of NO 2 -FA distribution is an initial esterification into complex lipids. Quantitative analysis …
Mass spectrometry-based study defines the human urine nitrolipidome
… , but their detection and characterization lagged. Several different nitrated fatty acid species
have been reported in animals and humans, but their formation remains controversial, and a …
have been reported in animals and humans, but their formation remains controversial, and a …