[HTML][HTML] Association study and a systematic meta-analysis of the VNTR polymorphism in the 3′-UTR of dopamine transporter gene and attention-deficit hyperactivity …

E Grünblatt, AM Werling, A Roth, M Romanos… - Journal of Neural …, 2019 - Springer
… We found no significant association between 10-repeat … ADHD population, as well as after
stratifying to adult ADHD (… and adolescent ADHD resulted in a nominal significant association (…

[HTML][HTML] Functional validation of CHMP7 as an ADHD risk gene

C Dark, C Williams, MA Bellgrove, Z Hawi… - Translational …, 2020 - nature.com
… charged multivesicular body protein 7 (CHMP7 7 ). In addition… is alleviated by treatment with
methylphenidate, contributing … large number of candidate genes for ADHD that have recently …

[HTML][HTML] Large epigenome-wide association study of childhood ADHD identifies peripheral DNA methylation associated with disease and polygenic risk burden

MA Mooney, P Ryabinin, B Wilmot, P Bhatt… - Translational …, 2020 - nature.com
non-sequence-based (ie, regulatory) genomic variation in neuropsychiatric phenotypes 5,6,7
been associated with blood pressure response to methylphenidate 69 . This SNP, …

[HTML][HTML] Associations between CES1 variants and dosing and adverse effects in children taking methylphenidate

JT Brown, N Beery, A Taran, T Stevens… - Frontiers in …, 2023 - frontiersin.org
… 0–17 years of age (6, 7). Despite its widespread usage, a fair … testing in children with ADHD
has proven challenging. … and CES1 genetic variation, we did identify several CES1 SNVs …

[HTML][HTML] Influence of COMT (rs4680) and DRD2 (rs1076560, rs1800497) Gene Polymorphisms on Safety and Efficacy of Methylphenidate Treatment in Children with …

M Śmiarowska, B Brzuchalski, E Grzywacz… - International Journal of …, 2022 - mdpi.com
Genetic variation in enzymes that act on the biosynthesis or … the effectiveness of MPH in
ADHD treatment [41]. Catechol-O-… of MPH treatment affected less than 7% of ADHD patients. …

Meta-analysis and systematic review of ADGRL3 (LPHN3) polymorphisms in ADHD susceptibility

EM Bruxel, CR Moreira-Maia… - Molecular …, 2021 - nature.com
genes, a region known as the NTAD gene cluster, increased in more than twofold the risk
of ADHD, influenced methylphenidate treatment response … symptoms in adult ADHD in a 7-year …

Genetics and pharmacogenetics of attention deficit hyperactivity disorder in childhood and adulthood

C Bonvicini, C Maj, C Scassellati - Personalized Psychiatry, 2020 - Elsevier
… based on common genetic variants, being not restricted to a … the association between these
candidate genes and ADHD. … SLC6A3 gene in relation to the response to methylphenidate. …

[HTML][HTML] Glutamate receptor genetic variants affected peripheral glutamatergic transmission and treatment induced improvement of Indian ADHD probands

M Chatterjee, S Saha, S Shom, N Dutta, S Sinha… - Scientific Reports, 2023 - nature.com
… Since ADHD probands are often treated with methylphenidate … with ADHD probands, twins,
adopted children, candidate genes… (60–90%) 7 indicates a strong genetic component in the …

The involvement of the canonical Wnt‐signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta‐analysis

E Grünblatt, Z Nemoda, AM Werling… - … of Medical Genetics …, 2019 - Wiley Online Library
… that methylphenidate activates Wnt-signaling (Grünblatt et al., 2018), we suggest that
LRP5/6 coreceptors could be regarded as possible new therapeutic targets in ADHD treatment, …

Stress-related genetic components in attention-deficit/hyperactivity disorder (ADHD): effects of the SERPINA6 and SERPINA1 genetic markers in a family-based …

MX Carpena, KY Sánchez-Luquez… - Journal of Psychiatric …, 2022 - Elsevier
… categories vary from 1 to 7 based on the level of functional … collect information on non-coding
genetic variants for the most … The relationship between genetic variation, gene expression …