Biliary atresia and cholestasis plasma non-targeted metabolomics unravels perturbed metabolic pathways and unveils a diagnostic model for biliary atresia
B Du, K Mu, M Sun, Z Yu, L Li, L Hou, Q Wang, J Sun… - Scientific Reports, 2024 - nature.com
… Enrichment analysis revealed 10 distinct metabolic pathways that differed… bile acid
biosynthesis. A total of 18 biomarkers were identified through biomarker analysis, and in combination …
biosynthesis. A total of 18 biomarkers were identified through biomarker analysis, and in combination …
Targeted metabolomics analysis of bile acids in patients with idiosyncratic drug-induced liver injury
Z Xie, L Zhang, E Chen, J Lu, L Xiao, Q Liu, D Zhu… - Metabolites, 2021 - mdpi.com
… metabolomics to identify and quantify specific types of bile … Together, these three bile acids
had an AUROC of 0.895 for … assay seems preferable to a non-targeted metabolomics assay…
had an AUROC of 0.895 for … assay seems preferable to a non-targeted metabolomics assay…
Effects of exercise on NAFLD using non-targeted metabolomics in adipose tissue, plasma, urine, and stool
AF Babu, S Csader, V Männistö, MM Tauriainen… - Scientific Reports, 2022 - nature.com
… a non-targeted metabolomics approach to identify metabolic … Our metabolomics investigation
combined with the pathway … reduce bile acid synthesis while increasing bile acid absorption …
combined with the pathway … reduce bile acid synthesis while increasing bile acid absorption …
Targeted metabolomics analysis of bile acids and cell biology studies reveal the critical role of glycodeoxycholic acid in buffalo follicular atresia
Y Wei, J Cheng, M Luo, S Yang, Q Xing… - The Journal of Steroid …, 2022 - Elsevier
… non-targeted metabolomics revealed the differences in bile … Aliquots of each bile acid standard
solution were mixed, diluted … Thirteen differential subspecies of bile acids were identified …
solution were mixed, diluted … Thirteen differential subspecies of bile acids were identified …
Integration of transcriptomics and non-targeted metabolomics reveals the underlying mechanism of follicular atresia in Chinese buffalo
J Cheng, Y Pan, S Yang, Y Wei, Q Lv, Q Xing… - The Journal of steroid …, 2021 - Elsevier
… Recently, combining transcriptomics and metabolomics to … of the transcriptomic analysis
did not identify any DEGs that … As we all know, bile acids are cytotoxic molecules which can …
did not identify any DEGs that … As we all know, bile acids are cytotoxic molecules which can …
… and validation of diagnostic biomarkers for intrahepatic cholestasis of pregnancy based on untargeted and targeted metabolomics analyses of urine metabolite …
W Liu, L Chen, K Miao, Y You, J Li, J Lu… - BMC Pregnancy and …, 2023 - Springer
… and elevated total serum bile acids, with other hepatobiliary … and untargeted metabolomics
and identified two underlying … in metabolomics: targeted metabolomics and non-targeted …
and identified two underlying … in metabolomics: targeted metabolomics and non-targeted …
Untargeted and Targeted Metabolomics Reveal the Underlying Mechanism of Aspirin Eugenol Ester Ameliorating Rat Hyperlipidemia via Inhibiting FXR to Induce …
L Xiao-Rong, M Ning, L Xi-Wang, L Shi-Hong… - Frontiers in …, 2021 - frontiersin.org
… was corrected by bile acid standard, and the metabolites were identified. Statistical Analysis
… tryptophan belonging to the amino acid metabolism pathway were also clustered together. …
… tryptophan belonging to the amino acid metabolism pathway were also clustered together. …
… lidan formula ameliorates α-naphthylisothiocyanate-induced intrahepatic cholestatic liver injury in rats as revealed by non-targeted and targeted metabolomics
R Zhang, T Huang, Q Zhang, Y Yao, C Liu, C Lin… - … and Biomedical Analysis, 2020 - Elsevier
… non-targeted metabolomics approach based on UHPLC-Q-TOF-MS/MS combined with a bile
acids (BAs) - targeted metabolomics … total of 39 potential biomarkers were identified in ANIT-…
acids (BAs) - targeted metabolomics … total of 39 potential biomarkers were identified in ANIT-…
Metabolomics analysis of serum in pediatric nephrotic syndrome based on targeted and non-targeted platforms
J Guo, J Zhao, R Liu, J Yu, M Zhang, H Wang, L Liu - Metabolomics, 2021 - Springer
… , canavalioside and uroporphyrin were identified to establish … , amino acid metabolism,
bile acid biosynthesis, linoleate … Therefore, the non-targeted metabolomics analysis was also …
bile acid biosynthesis, linoleate … Therefore, the non-targeted metabolomics analysis was also …
[PDF][PDF] High‐resolution exposomics and metabolomics reveals specific associations in cholestatic liver diseases
DI Walker, BD Juran, AC Cheung… - Hepatology …, 2022 - Wiley Online Library
… as a generalizable approach to identify potentially pathogenic … enrichment analysis found
that the bile acid biosynthesis … analysis of large- scale, non- targeted metabolomics data. BMC …
that the bile acid biosynthesis … analysis of large- scale, non- targeted metabolomics data. BMC …