Current concepts and novel targets for antiplatelet therapy

M Gawaz, T Geisler, O Borst - Nature Reviews Cardiology, 2023 - nature.com
… patient care and have facilitated more individualized therapy. Finally, we discuss novel
therapeutic targets and compounds for antiplateletNovel approaches for antiplatelet therapy

Current and novel antiplatelet therapies for the treatment of cardiovascular diseases

G Jourdi, M Lordkipanidze, A Philippe… - International journal of …, 2021 - mdpi.com
… and safety of such a novel approach in acute settings where rapid platelet inhibition is
desirable, as for example in ACS patients [168,169]. Two other novel highly potent inhibitors of …

Novel antiplatelet therapies

K Kolandaivelu, DL Bhatt - Platelets, 2019 - Elsevier
… To overcome these issues, novel approaches to ADP-axis inhibition have been explored.
Most notable are the direct P2Y 12 inhibitors, which were developed after explicit knowledge of …

Novel antiplatelet therapies for atherothrombotic diseases

A Majithia, DL Bhatt - Arteriosclerosis, thrombosis, and vascular …, 2019 - Am Heart Assoc
… Current approaches to improving antiplatelet efficacy have relied … novel approaches for
antiplatelet therapies are being developed. Instead of simply developing more potent therapies, …

Novel approaches to P2Y12 inhibition and aspirin dosing

WAE Parker, RF Storey - Platelets, 2021 - Taylor & Francis
… Subsequently, a multi-center phase 2 double-blind randomized controlled trial (RCT) of
patients with a history of ischemic heart disease already receiving antiplatelet therapy with …

Novel antiplatelet targets in the treatment of acute coronary syndromes

FO Alenazy, MR Thomas - Platelets, 2021 - Taylor & Francis
… antagonism of novel targets involved in platelet function could shape future antiplatelet
therapies that could ultimately lead to more effective or safer therapeutic approaches. In this …

[HTML][HTML] Antiplatelet therapy for atherothrombotic disease in 2022—from population to patient-centered approaches

G Jourdi, A Godier, M Lordkipanidzé… - Frontiers in …, 2022 - frontiersin.org
antiplatelet therapeutic and prophylactic strategies. The shift from a population-based approach
… associated with the different antiplatelet strategies, so that the right patient gets the right …

Antiplatelet therapy in cardiovascular disease: Current status and future directions

G Passacquale, P Sharma, D Perera… - British Journal of …, 2022 - Wiley Online Library
… dual therapy. We will also touch on the place of anticoagulation on top of antiplatelet therapy
in … Finally, we will consider whether personalised approaches to antiplatelet therapy may be …

Novel antiplatelet agents in cardiovascular disease

M Tscharre, AD Michelson… - Journal of …, 2020 - journals.sagepub.com
antiplatelet therapy. This review focuses on new antiplatelet drugs in development … a
potentially superior efficacy and safety profile compared to currently available therapies. …

Antiplatelet therapy in acute coronary syndromes. Lights and shadows of platelet function tests to guide the best therapeutic approach

G Cimmino, E Gallinoro, L Di Serafino… - Current Vascular …, 2020 - ingentaconnect.com
… Thus, antiplatelet therapy with drugs able to interfere with … platelet reactivity, despite
antiplatelet therapy, is associated … Thus, antiplatelet therapy represents a cornerstone of ACS …