Pharmacological profile of AZD8871 (LAS191351), a novel inhaled dual M3 receptor antagonist/β2-adrenoceptor agonist molecule with long-lasting effects and …

M Aparici, C Carcasona, I Ramos, JL Montero… - … of Pharmacology and …, 2019 - ASPET
… in development for chronic obstructive pulmonary disease. This … None of the patients had a
history of asthma. The protocol … rate at efficacious and long-acting doses, which confirmed the …

Pharmacology and therapeutics of bronchodilators revisited

MG Matera, CP Page, L Calzetta, P Rogliani… - Pharmacological …, 2020 - ASPET
… as asthma and chronic obstructive pulmonary disease (COPD). … classes of bronchodilator
and in identifying novel classes of … inhaled long-acting β 2 -adrenoceptor agonists (LABAs) and …

Long-acting bronchodilator use in chronic obstructive pulmonary disease in primary care in New Zealand: a retrospective study of treatment patterns and evolution …

D Milea, SH Yeo, Y Nam… - … of Chronic Obstructive …, 2021 - Taylor & Francis
COPD reported that triple therapy was the most common treatment regimen at admission.
Citation30 Variations in asthma … stratify our results by COPD and/or asthma diagnosis, but this …

… long-acting β2-agonist plus inhaled long-acting muscarinic antagonist vs inhaled long-acting β2-agonist plus inhaled corticosteroid fixed-dose combinations in COPD …

MT Wang, JH Lai, YL Huang, JT Liou, SH Cheng… - Chest, 2021 - Elsevier
long-acting β 2 agonist (LABA) combined with a long-acting … for managing moderate to
severe COPD. Since 2017, the … with a history of asthma or asthma-COPD overlap or with a blood …

Dual bronchodilator versus inhaled corticosteroid/long-acting β2-agonist in patients with chronic obstructive pulmonary disease: a meta-analysis of randomized …

H Chen, K Wang, T Yuan, X Wang, L Huanng… - International …, 2021 - Elsevier
… treatments for COPD patients, including long-acting muscarinic antagonist (LAMA), long-acting
β2-… Patients with asthma, other respiratory disorders, such as bronchiectasis or unclear …

Comparison of effectiveness using different dual bronchodilator agents in chronic obstructive pulmonary disease treatment

SL Cheng - Journal of Clinical Medicine, 2021 - mdpi.com
… Olodaterol (OLO) is a novel once-daily LABA bronchodilator that was effective in lung … dual
long-acting bronchodilators (UME/VIL, IND/GLY, and TIO/OLO) used on patients with COPD

Bronchodilator reversibility in asthma and COPD: findings from three large population studies

C Janson, A Malinovschi, AFS Amaral… - European …, 2019 - Eur Respiratory Soc
… The participants were asked to refrain from using short-acting β 2 -agonists for ≥6 h, long-acting
β 2 -agonists for 12 h and long-acting antimuscarinic agents for 24 h before performing …

[HTML][HTML] Inhaled long-acting muscarinic antagonists in asthma–A narrative review

A Papi, LM Fabbri, HAM Kerstjens, P Rogliani… - European journal of …, 2021 - Elsevier
Long-acting muscarinic antagonists (LAMAs) have a recognised role in the … of chronic
obstructive pulmonary disease. In asthma, muscarinic antagonists (both short- and long-acting) …

Current evidence for COPD management with dual long-acting muscarinic antagonist/long-acting β2-agonist bronchodilators

NS Skolnik, TS Nguyen, A Shrestha, R Ray… - Postgraduate …, 2020 - Taylor & Francis
… Short-acting bronchodilators are indicated as monotherapy in patients … long-acting
bronchodilators are recommended as initial maintenance therapy for patients with a history of …

Management of asthma COPD overlap

DJ Maselli, NA Hanania - Annals of Allergy, Asthma & Immunology, 2019 - Elsevier
… in patients with asthma with the use of long-acting 2 agonist … to include a long-acting
bronchodilator in conjunction with … in both asthma and COPD has led to the identification of novel