A randomized, noninferiority trial comparing ICS+ LABA with ICS+ LABA+ LAMA in asthma-COPD overlap (ACO) treatment: the ACO Treatment with Optimal …

SY Park, S Kim, JH Kim, SH Kim, T Lee… - The Journal of Allergy …, 2021 - Elsevier
… patients with either asthma or COPD. Most patients … COPD. Patients with ACO also present
with more severe symptoms than do those with asthma or COPD, and may require long-acting

… /formoterol fumarate metered dose inhaler in comparison with other long-acting muscarinic antagonist/long-acting β2-agonist fixed-dose combinations in COPD

MK Siddiqui, P Shukla, M Jenkins… - Therapeutic …, 2019 - journals.sagepub.com
… Dual bronchodilation with a long-acting muscarinic antagonist (LAMA)/long-acting β 2 -… an
established treatment strategy for chronic obstructive pulmonary disease (COPD). The relative …

Single-inhaler triple versus dual bronchodilator therapy in COPD: real-world comparative effectiveness and safety

S Suissa, S Dell'Aniello, P Ernst - … Obstructive Pulmonary Disease, 2022 - Taylor & Francis
… , we regrouped the three baseline long-acting bronchodilator groups into two categories,
any … included COPD patients with a history of asthma and with multiple COPD exacerbations, …

Triple inhaler versus dual bronchodilator therapy in COPD: real-world effectiveness on mortality

S Suissa, S Dell'Aniello, P Ernst - … Obstructive Pulmonary Disease, 2022 - Taylor & Francis
COPD, we excluded all patients less than 50 years of age on the date of their initial prescription
for these long-acting bronchodilators… history of asthma and multiple COPD exacerbations…

[HTML][HTML] … effects of AZD8999, a novel bifunctional muscarinic acetylcholine receptor antagonist/β2-adrenoceptor agonist (MABA) compound in neutrophils from COPD …

J Milara, S Contreras, A de Diego, M Calbet, M Aparici… - Plos one, 2019 - journals.plos.org
… The current first-line maintenance treatment for COPD involves the use of bronchodilators,
including long-acting muscarinic acetylcholine receptor antagonists (LAMAs) and long-acting

[HTML][HTML] Long-acting maintenance pharmacotherapy in chronic obstructive pulmonary disease

EM Harrison, V Kim - Respiratory Medicine: X, 2019 - Elsevier
… Aerosphere® is a novel delivery technology in which drug crystals adhere to phospholipids
to form … Furthermore, some patients with COPD show clinical overlap with asthma, which may …

[HTML][HTML] … inhaler extrafine triple therapy versus inhaled corticosteroid plus long-acting beta2 agonist in eastern Asian patients with COPD: the TRIVERSYTI randomised …

J Zheng, S Baldi, L Zhao, H Li, KH Lee, D Singh… - Respiratory …, 2021 - Springer
… Main exclusion criteria were: diagnosis of asthma; COPD exacerbation in the four weeks
prior to entry; or use of traditional Chinese medicines for respiratory diseases. Patients provided …

Characteristics of Patients with Chronic Obstructive Pulmonary Disease Treated with Long-Acting Bronchodilators in a Real-World Setting in Singapore: A Single …

M Sim, A Yii, X Xu, P Bahety, CH Loh… - … of Chronic Obstructive …, 2022 - Taylor & Francis
… pre-bronchodilator FEV 1 % predicted) were taken from the most recent values before the
index date. Variables recorded at baseline included asthma diagnosis, COPD Assessment …

Bronchodilator reversibility in asthma and COPD: findings from three large population studies

C Janson, A Malinovschi, AFS Amaral… - European …, 2019 - Eur Respiratory Soc
… The participants were asked to refrain from using short-acting β 2 -agonists for ≥6 h, long-acting
β 2 -agonists for 12 h and long-acting antimuscarinic agents for 24 h before performing …

[HTML][HTML] … , a once-daily, lung-selective, long-acting muscarinic antagonist for nebulized therapy of chronic obstructive pulmonary disease: evaluation in phase 3 clinical …

JF Donohue, G Feldman, S Sethi, CN Barnes… - Pulmonary …, 2019 - Elsevier
… Compared with those without COPD, patients with COPD are known to have a more than …
long-acting muscarinic antagonist (LAMA) and long-acting beta agonist (LABA) use for COPD