[HTML][HTML] Comparison of effectiveness using different dual bronchodilator agents in chronic obstructive pulmonary disease treatment

SL Cheng - Journal of Clinical Medicine, 2021 - mdpi.com
… Olodaterol (OLO) is a novel once-daily LABA bronchodilator that was effective in lung … dual
long-acting bronchodilators (UME/VIL, IND/GLY, and TIO/OLO) used on patients with COPD

Pharmacological profile of AZD8871 (LAS191351), a novel inhaled dual M3 receptor antagonist/β2-adrenoceptor agonist molecule with long-lasting effects and …

M Aparici, C Carcasona, I Ramos, JL Montero… - … of Pharmacology and …, 2019 - ASPET
… in development for chronic obstructive pulmonary disease. This … None of the patients had a
history of asthma. The protocol … rate at efficacious and long-acting doses, which confirmed the …

Inhaled corticosteroids in COPD: trying to make a long story short

C Tantucci, L Pini - … of Chronic Obstructive Pulmonary Disease, 2020 - Taylor & Francis
COPD suggesting their adoption in the chronic treatment of COPD combined with long-acting
bronchodilators … of both asthma and COPD, Citation61 namely subjects with a history of …

[HTML][HTML] … safety, tolerability, pharmacokinetics, and pharmacodynamics of single ascending doses of this novel inhaled long-acting dual-pharmacology bronchodilator

E Jimenez, C Astbury, M Albayaty… - Respiratory …, 2020 - Springer
… developed for use in COPD. Further studies would be required to confirm the efficacy of
navafenterol in patients with COPD and in patients with severe asthma in combination with an …

Stepwise management of COPD: What is next after bronchodilation?

M Miravitlles, K Matsunaga… - Therapeutic Advances in …, 2023 - journals.sagepub.com
… for COPD recommends that the majority of patients are initially treated with a long-acting
bronchodilator … 2 inflammation biomarker to confirm asthma-like features in patients with COPD. …

Pharmacological treatment of stable COPD: need for a simplified approach

G Hillas, A Papaporfyriou, K Dimakou… - Postgraduate …, 2020 - Taylor & Francis
… Most of the novel therapeutic agents result from the … ICS withdrawal in COPD patients with
an asthmatic component is related … Long-acting bronchodilators are the central part of COPD

Targeting the small airways with inhaled corticosteroid/long-acting beta agonist dry powder inhalers: a functional respiratory imaging study

H Watz, S Barile, D Guastalla, E Topole… - Journal of aerosol …, 2021 - liebertpub.com
… periphery) of ICS/LABA with NEXThaler in healthy volunteers, and patients with asthma
and COPD using a gamma-scintigraphy technique, (41) supporting the validity of our findings. …

[HTML][HTML] … : safety, tolerability and pharmacokinetics of multiple ascending doses of this novel inhaled, long-acting, dual-pharmacology bronchodilator, in two phase I …

V Balaguer, M Albayaty, E Jimenez… - Respiratory …, 2020 - Springer
Chronic obstructive pulmonary disease (COPD) and asthma … 3.2 million deaths from COPD
and 0.4 million from asthma [1], … , and bronchodilator therapy is a key component of this. In …

Bronchodilators for hyperinflation in COPD associated with biomass smoke: clinical trial

A Ramírez-Venegas, M Velázquez-Uncal… - … obstructive pulmonary …, 2019 - Taylor & Francis
… -COPD, our results showed that patients with BE-COPD might receive additional benefit from
regular treatment with long-acting bronchodilators … and long-acting bronchodilator effects. …

A pooled analysis of mortality in patients with COPD receiving dual bronchodilation with and without additional inhaled corticosteroid

M Miravitlles, K Verhamme, PMA Calverley… - … obstructive pulmonary …, 2022 - Taylor & Francis
COPD, including long-acting bronchodilators (long-acting muscarinic antagonists [LAMAs]
and/or long-acting … history of asthma, whereas patients with a history of asthma were excluded …