[HTML][HTML] Novel therapeutic targets for amyotrophic lateral sclerosis

G Batra, M Jain, RS Singh, AR Sharma… - Indian Journal of …, 2019 - journals.lww.com
Amyotrophic lateral sclerosis (ALS) is an untreatable and fatal neurodegenerative disease
that is identified by the loss of motor neurons in the spinal cord, brain stem, and motor cortex
which theatrically reduces life expectancy. Although the primary cause of ALS remains
unclear, its heterogeneity put forward for consideration of association with various factors,
including endogenous and/or environmental ones, which may be involved in progressive
motor neuron stress that causes activation of different cell death pathways. It is hypothesized …
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