Polyadenylation and nuclear export of mRNAs
M Stewart - Journal of Biological Chemistry, 2019 - ASBMB
… mRNA nuclear export and how it is integrated into the nuclear phase of the gene expression
pathway. Nuclear export … , such as proteins and RNAs, between the cytoplasmic and nuclear …
pathway. Nuclear export … , such as proteins and RNAs, between the cytoplasmic and nuclear …
New progresses of circular RNA biology: from nuclear export to degradation
… Once produced in the nucleus, the majority of circular RNAs are exported to the cytoplasm …
RNAs and highlight the recent advances in our understanding of circular RNA nuclear export …
RNAs and highlight the recent advances in our understanding of circular RNA nuclear export …
Mechanisms of nuclear mRNA export: A structural perspective
Y Xie, Y Ren - Traffic, 2019 - Wiley Online Library
… reduces the nuclear export of CTE-RNA in vivo, … ) RNA export. One hypothesis is that the
higher-order NXF1•NXT1 assembly may facilitate nuclear export of a subset of structured RNAs, …
higher-order NXF1•NXT1 assembly may facilitate nuclear export of a subset of structured RNAs, …
Gene architecture and sequence composition underpin selective dependency of nuclear export of long RNAs on NXF1 and the TREX complex
… export of virtually all polyadenylated RNAs. Here, we depleted different proteins that act in
nuclear export in human cells and quantified the transcriptome-wide consequences on RNA …
nuclear export in human cells and quantified the transcriptome-wide consequences on RNA …
Mechanisms of long noncoding RNA nuclear retention
… RMRP (RNA component of mitochondrial RNA-processing endoribonuclease) is localized
… the nuclear DNA. RMRP binds to HuR (human antigen R) in the nucleus and is exported into …
… the nuclear DNA. RMRP binds to HuR (human antigen R) in the nucleus and is exported into …
The nuclear export protein XPO1—from biology to targeted therapy
AS Azmi, MH Uddin, RM Mohammad - Nature reviews Clinical oncology, 2021 - nature.com
… The main physiological function of exportin 1 (XPO1) is the export of proteins and small
nuclear RNAs from the nucleus to the cytoplasm. XPO1 overexpression leads to greater levels of …
nuclear RNAs from the nucleus to the cytoplasm. XPO1 overexpression leads to greater levels of …
The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine–containing mRNAs
… may affect the nuclear export of m 6 A-modified RNA targets. … FMRP facilitates the nuclear
export of RNA transcripts, but … using nascent RNA from the whole-cell rather than nuclear or …
export of RNA transcripts, but … using nascent RNA from the whole-cell rather than nuclear or …
Targeting of nucleo‑cytoplasmic transport factor exportin 1 in malignancy
… nuclear‑cytoplasmic transport of protein, ribosomal RNA and certain required mRNAs for
ribosomal biogenesis. Furthermore, XPO1‑mediated nuclear export is … ‑mediated nuclear export …
ribosomal biogenesis. Furthermore, XPO1‑mediated nuclear export is … ‑mediated nuclear export …
Inhibitors of nuclear transport
DA Jans, AJ Martin, KM Wagstaff - Current opinion in cell biology, 2019 - Elsevier
… was later shown to be a nuclear export inhibitor specifically targeting EXP1 and in … nuclear
export of various proteins, including signalling molecules such as mitogen activated protein …
export of various proteins, including signalling molecules such as mitogen activated protein …
Specialization of the Drosophila nuclear export family protein Nxf3 for piRNA precursor export
… export mediated by nuclear export factor 1 (Nxf1). Although UAP56, a component of the
transcription and export … Quantification of RNA-FISH was performed by counting nuclear and …
transcription and export … Quantification of RNA-FISH was performed by counting nuclear and …
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